Over the past decade, cross-docking has emerged as an important material handling technology in transportation. A variation of the well-known Vehicle Routing Problem (VRP), the Vehicle Routing Problem with Cross-Docking (VRPCD) arises in a number of logistics planning contexts. This paper addresses the VRPCD, where a set of homogeneous vehicles are used to transport products from the suppliers ...

Chemical cross-links identified by mass spectrometry generate distance restraints that reveal low-resolution structural information on proteins and protein complexes. The technology to reliably generate such data has become mature and robust enough to shift the focus to the question of how these distance restraints can be best integrated into molecular modeling calculations. Here, we introduce ...

With the knowledge accumulated from participating the first cross-docking network development, this paper summarizes the key planning and modeling issues for the crossdocking operations of a large supermarket retail chain in Taiwan. The insights gained from this study can aid large retail chains to better plan their cross-docking operations.

We have determined the three-dimensional structure of the protein complex between latexin and carboxypeptidase A using a combination of chemical cross-linking, mass spectrometry and molecular docking. The locations of three intermolecular cross-links were identified using mass spectrometry and these constraints were used in combination with a speed-optimised docking algorithm allowing us to eva...

Cross-docking is a logistic concept, which plays an important role in supply chain management by decreasing inventory holding, order packing, transportation costs and delivery time. Paying attention to these concerns, and importance of the congestion in cross docks, we present a mixed-integer model to optimize the location and design of cross docks at the same time to minimize the total transpo...

Prediction of the bound configuration of small-molecule ligands that differ substantially from the cognate ligand of a protein co-crystal structure is much more challenging than re-docking the cognate ligand. Success rates for cross-docking in the range of 20-30 % are common. We present an approach that uses structural information known prior to a particular cutoff-date to make predictions on l...

This paper proposes an integrated network design model for a post-distribution cross-docking strategy, comprising multi product production facilities with shared production resources, capacitated cross docks with setup cost and customer zones with time windows constraints. The model is dynamic in terms of time-varying uncertain demands, whereas uncertainty is expressed with scenario approach an...

Library organizations in the Netherlands show an increasing interest to employ depots for low-cost storage and demand fulfillment of item requests. Typically, all libraries organization have a shared catalog, and, on local unavailability, requests can be shipped from elsewhere organization. The depot used consolidate shipment by making tours along libraries, delivering requested items, but also...