Gold nanoparticles synthesized via sodium citrate reduction of chloroauric acid (HAuCl(4)) were functionalized with either various concentrations of thiol-terminated Bodipy(®) FL L-cystine (0.5, 1.0, 1.5, and 2.0 μg/mL) or Bodipy-poly(ethylene glycol) at concentrations of 0.5-18.75, 1.0-12.50, and 1.5-6.25 μg/mL to form a mixed monolayer of BODIPY-PEG. Thiol-terminated Bodipy, a fluorescing mol...

Glyco-functionalized gold nanoparticles have great potential as biosensors and as inhibitors due to their increased binding to carbohydrate-recognizing receptors such as the lectins. Here we apply previously developed solid phase polymer synthesis to obtain a series of precision glycomacromolecules that allows for straightforward variation of their chemical structure as well as functionalizatio...

Green synthesis of gold nanoparticles using plant extracts is one of the more promising approaches for obtaining environmentally friendly nanomaterials for biological applications and environmental remediation. In this study, proanthocyanidins-functionalized gold nanoparticles were synthesized via a hydrothermal method. The obtained gold nanoparticles were characterized by ultraviolet and visib...

The present study synthesizes a novel adsorbent by coating Fe3O4 magnetic nanoparticles with amino functionalized mesoporous silica. The FTIR spectrums indicate that silica has been successfully coated on the surface of Fe3O4 and 3-aminopropyl tri methoxysilane compound have been grafted to the surface of silica-coated Fe3O4. The XRD analysis shows the presence of magnetite phase with cubic spi...

A novel method to produce solution-phase triangular silver nanoparticles is presented. Ag nanoparticles are prepared by nanosphere lithography and are subsequently released into solution. The resulting nanoparticles are asymmetrically functionalized to produce either single isolated nanoparticles or dimer pairs. The structural and optical properties of Ag nanoparticles have been characterized. ...

Formation of gold nanoparticles in aqueous ethanol in the presence of pyridine-functionalized single-chain nanoparticles allows for the fast and highly sensitive colorimetric detection of zein corn protein.

Targeted metallic nanoparticles have shown promise as contrast agents for molecular imaging. To obtain molecular specificity, the nanoparticle surface must be appropriately functionalized with probe molecules that will bind to biomarkers of interest. The aim of this study was to develop and characterize a flexible approach to generate molecular imaging agents based on gold nanoparticles conjuga...

Functionalized gold nanoparticles bind selectively to cytochrome c or cytochrome c peroxidase and inhibit enzyme turnover.

The fabrication and characterization of template silver nanoshell structures and the encapsulation of gold nanoparticles using biocompatible poly(oxyethylene)-poly(butylene) diblock co-polymer vesicles is described in this work. These vesicles have a narrow diameter size distribution around 200 nm. Silver nanoparticles (Ø = 1-10 nm) functionalized with decanethiol were successfully entrapped in...

We report on the functionalization of ligand-free NaGdF(4):Er(3+), Yb(3+) upconverting nanoparticles with heparin and basic fibroblast growth factor (bFGF). These upconverting nanoparticles are used to obtain high-contrast images of HeLa cells. These images reveal that the heparin-bFGF functionalized nanoparticles show specific binding to the cell membrane.