In humans, orally administered 4-(5-pyridin-4-yl-1H-[1,2,4]triazol-3-yl) pyridine-2-carbonitrile (FYX-051) is excreted mainly as triazole N(1)- and N(2)-glucuronides in urine. It is important to determine the enzyme(s) that catalyze the metabolism of a new drug to estimate individual differences and/or drug-drug interactions. Therefore, the characterization and mechanism of these glucuronidatio...

in this study, a new and valuable forage source was introduced with combination and silage of alfa-alfa, halocnemum and mesquite via chemical, gas production and in vivo methods. to perform this research, first the right amounts of the species were collected. then they were cut by chopper to the dimensions of less than 5 cm. then, halocnemum, mesquite fruit, alfalfa and molasses were silaged ac...

Gabriele Grandi 1,*, Jelena Loncarski 2 and Milan Srndovic 1 1 Department of Electrical, Electronic, and Information Engineering, University of Bologna, Viale Risorgimento 2, Bologna 40136, Italy; [email protected] 2 Department of Engineering Sciences, Ångström Laboratory, Uppsala University, Lägerhyddsvägen 1, Box 534, Uppsala S-751 21, Sweden; [email protected] * Correspo...

The environment in which foods are prepared and handled can have significant impact on microbiological safety and quality, particularly for ready-to-eat foods. Outbreaks associated with Listeria monocytogenes and salmonellae have led to an increasing awareness that certain pathogens can persist in food processing environments, contaminate foods as they are being processed and lead to foodborne ...

in order to determine the diet of dalagh sheep, winter rangeland of gomishan plain was selected. after delineating of the grazingland territory, rangeland condition and plant combination was determined by range value method and range trend was obtained by trend balance method. time of bite-count record was done in morning and afternoon in a five-day period; first week of november (1389) and las...