نتایج جستجو برای: igg2a
تعداد نتایج: 1866 فیلتر نتایج به سال:
A Sabin 1 strain poliovirus (PV) mutant, S1(2Y-1I), carrying a Tyr at amino acid position VP2(142) and an Ile at position VP1(160), can establish persistent infections in HEp-2c cells. This mutant forms atypical 147S particles upon interaction at 0 degrees C with either cells expressing PV receptor (PVR) CD155, or PVR-IgG2a, a chimeric molecule consisting of an extracellular moiety of PVR and t...
Using three different Fc g receptor (Fc g R)-deficient mouse strains, we examined the induction of autoimmune hemolytic anemia by each of the four immunoglobulin (Ig)G isotype-switch variants of a 4C8 IgM antierythrocyte autoantibody and its relation to the contributions of the two Fc g R, Fc g RI, and Fc g RIII, operative in the phagocytosis of opsonized particles. We found that the four IgG i...
The phagocytosis of Trypanosoma musculi by macrophages in the presence of specific antibodies was investigated. In 14-day-infected mice, opsonic antibodies were detected in serum, and phagocytosis of parasites by peritoneal macrophages was observed. The mechanism of T. musculi phagocytosis was analyzed. The binding of trypanosomes to peritoneal macrophages and J774 cells was observed in the pre...
In vivo treatment of mice with the natural killer T (NKT) cell ligand, alpha-galactosylceramide (alphaGalCer), ameliorates autoimmune diabetes and experimental autoimmune encephalomyelitis (EAE) by shifting pathogenic Th1-type immune responses to nonpathogenic Th2-type responses. In the current study, in vivo activation of NKT cells in adult NZB/W mice by multiple injections of alphaGalCer indu...
Background: There are reports on the ability of chitin microparticles to modulate the TH1 and TH2 responses, depending on the size and administration route. The purpose of the present study was to investigate the immunoadjuvant effects of the small-sized (less than 40 microns) chitin microparticles (CMP) in vaccination against Leishmania major for preventing leishmaniasis in BALB /c mice by ...
زمینه و اهداف: بروسلوزیس یک بیماری مشترک بین انسان و حیوان میباشد و ارزیابی آنتیژنهای مختلف آن ازنظر پاسخهای ایمونولوژیکی و بررسی استراتژیهای مختلف ایمنسازی در طراحی واکسنهای مؤثر نقشی اساسی دارند. در این تحقیق هدف ما ارزیابی ایمونولوژیکی وکتور یوکاریوتی pVAX1 حامل ژن پروتئین غشای خارجی 31 کیلو دالتونی (Omp31) بروسلا ملی تنسیس بود. مواد و روش کار: در این مطالعه که در سال 1392 به انجام رس...
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