نتایج جستجو برای: k23

تعداد نتایج: 153  

Journal: :Sinkron : jurnal dan penelitian teknik informatika 2022

Evaluation of the quality employees in an institution is very necessary, especially for promotions which are rights every employee leading a company that full competition. The purpose this paper to contribute terms evaluation process selecting who ready be promoted particular institution. With support various parties, consistent and optimal method needed carry out process, popular priority, it ...

Journal: :Sleep 2023

Abstract Introduction Previous research has shown that approximately 78% of college students who suffer from insomnia also endorsed depressive symptoms. Students with depression were 9.5 times more likely to have than did not depression. There been evidence Cognitive Behavioral Therapy for Insomnia (CBT-I) can reduce However, the effectiveness a self-guided mobile version CBT-I (iCBT-I) in redu...

بختیاری, سالار, سایه میری, فاطمه, مشتاقی, سید علی اصغر,

Background and purpose: The E23K polymorphism of ATP-sensitive potassium channel kcnj11 gene leads to the conversion of glutamate to lysine amino acids and this substitution is associated with increased risk of several diseases such as diabetes. We aimed to examine the association between kcnj11 E23K variation and risk of type 2 diabetes mellitus (T2DM) in a Kurdish population. Materials and m...

ژورنال: تحقیقات اقتصادی 2012

در بیش‎تر کشورهای در حال توسعه،‎ بخش عمومی نقش مهمی در عملکرد بازار ایفا می‎کند. به طور معمول در این کشورها فعالیت‎های اقتصادی، رشد و توسعه‌، بدون دخالت دولت مختل می‎شود، اما گسترش بی‎حد و حصر دولت نیز مشکل آفرین است. دولت در تولید کالاهای عمومی و تنظیمات اقتصاد، دارای اختیار تصمیم‌گیری است. بوروکراسی فاسد با تکیه بر همین اختیار ایجاد می‌شود. کارکنان فاسد با دست‌کاری در مقررات و عرضه‌ی نامطلوب...

2017
Scott Cunningham Jason M. Lindo Caitlin Myers

We estimate the effects of abortion-clinic closures on clinic access and abortions using variation generated by Texas HB2, a “TRAP” law that shuttered nearly half of Texas’ abortion clinics in late 2013. Our results suggest a substantial and non-linear effect of distance to clinics. Increases from less than 50 miles to 50–100, 100–150, and 150–200 miles reduce abortion rates by 15, 25, and 40 p...

2013
David Choi Andrea Lowe John M. Olin Louis Kaplow

Regulation produces enormous benefits and costs, both of which are greatly influenced by myriad exemptions and preferences for small firms that contribute a significant minority of output in many sectors. These firms may generate a disproportionate share of harm due to their being exempt and because exemption induces additional harmful activity to be channeled their way. This article analyzes o...

2017
Ricardo Alfán-Guzmán Haluk Ertan Mike Manefield Matthew Lee

Dehalobacter sp. strain TeCB1 was isolated from groundwater near Sydney, Australia, that is polluted with a range of organochlorines. The isolated strain is able to grow by reductive dechlorination of 1,2,4,5-tetrachlorobenzene to 1,3- and 1,4-dichlorobenzene with 1,2,4-trichlorobenzene being the intermediate daughter product. Transient production of 1,2-dichlorobenzene was detected with subseq...

Journal: :Molecular and cellular biology 2000
T J Kelly S Qin D E Gottschling M R Parthun

Hat1p and Hat2p are the two subunits of a type B histone acetyltransferase from Saccharomyces cerevisiae that acetylates free histone H4 on lysine 12 in vitro. However, the role for these gene products in chromatin function has been unclear, as deletions of the HAT1 and/or HAT2 gene displayed no obvious phenotype. We have now identified a role for Hat1p and Hat2p in telomeric silencing. Telomer...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1999
A A Carmen P R Griffin J R Calaycay S E Rundlett Y Suka M Grunstein

Histone deacetylases such as human HDAC1 and yeast RPD3 are trichostatin A (TSA)-sensitive enzymes that are members of large, multiprotein complexes. These contain specialized subunits that help target the catalytic protein to histones at the appropriate DNA regulatory element, where the enzyme represses transcription. To date, no deacetylase catalytic subunits have been shown to have intrinsic...

2014
Ann Kristin Eriksson Jon Petter Gustafsson Dean Hesterberg

19 Phosphorus (P) losses from agricultural soils constitute a main driver for eutrophication of the 20 Baltic Sea. There is limited knowledge about sorption and release processes of P in these soils, 21 especially concerning the effects of fertilization. In this study, P speciation of the clay fractions 22 from six different soils in long-term fertility experiments in Sweden was investigated by...

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