due to an adenocarcinoma of the right upper lobe with infiltration of the main bronchus a 49-years-old female patient underwent an upper bilobectomy with sleeve resection. after two completed chemotherapy bouts and signs of sepsis another thoracotomy was inevitable.  as a complicating factor a supracarinal, necrotic and perforating lesion of the trachea appeared. the defect can be initially rep...

The difficulties encountered in dealing with the bone deficient acetabulum are amongst the greatest challenges in hip surgery. Acetabular reconstruction in revision total hip arthroplasty can successfully be achieved with hemispherical components featuring a porous or roughened ingrowth surface and options for placement of multiple screws for minor acetabular defect. Acetabular component select...

Introduction Banked allogeneic bone grafts have been used widely in clinic for the repair of bone defects. Massive allografts are thought to function through an osteoconductive pathways, demineralized bone was reported to be osteoinductive. Morselized allograft which has been used to fill bony defects in revision arthroplasty to fulfill a mechanical role, as well as to provide a scaffold for ne...

Background and Aim: Autogenous bone grafts are considered the gold standard although they have several disadvantages, leading to a search for suitable alternative graft biomaterials. This study evaluates the histological and histomorphometric properties of regenerated bone in defects in rabbits following the application of two commercially available xenografts (Bio-Oss and Osteon). Materials a...

Objective- The present study was aimed to evaluate repair of a critical segmental defect of rabbit femur using the rabbit’s femoral defects repaired by Zeolite and Zeolite/Collagen scaffolds Design- Experimental Study Animals- Forty-five mature male New Zealand white rabbits Procedures- The animals were randomly divided into three groups of 15 animals each. In the first group...

conclusions along with the technological advancement, different materials are employed according to the size of the cranium defect and the age of the case. the application of split costa cranioplasty for the small cranium defects in the region of patient’s face is the method with the least possibility of complications, and its cosmetic and functional results are quite promising. introduction os...

background: there are multiple methods for acceleration of bone healing. bone marrow has been shown to contain osteoprogenitor cells.   objective: to determine the effect of percutaneous bone marrow injection on bone healing.   methods: 15 mature, 2-kg-weighing white new zealand rabbits from both sexes were randomized into 3 groups: group i: only osteotomy of right radius was performed and a 5 ...

Background: Tissue engineering using Stem cell from Human Exfoliated Deciduous Teeth (SHED) and a natural biomaterials biomaterial scaffold has become a promising therapy for the alveolar bone defect. The aim of this study was to analyze the Osteoprotegerin (OPG) and Receptor Activator of NF-Κb ligand (RANKL) expression after the application of Hydroxyapatite scaffold and SHED.Methods: A labora...