The discovery of the medicinal properties gold complexes has fuelled design and synthesis new anticancer metallodrugs, which have received special attention due to their unique modes action. Current research in development compounds with therapeutic is predominantly focused on molecular drug leads superior pharmacological activities, e.g., by introducing targeting features. Moreover, intensive ...

A series of six Zn(II) tetraphenylporphyrins (ZnTPP), with a phenyl (P) or oligophenyleneethynylene (OPE = (PE) n ) rigid-rod bridge varying in length (9-30 A) and terminated with an isophthalic acid (Ipa) anchoring unit, were prepared as model dyes for the study of sensitization processes on metal oxide semiconductor nanoparticle surfaces (MO(n) = TiO(2), ZnO, and insulating ZrO(2)). The dyes ...

Abstract The kinetic characteristics, mechanisms of activity, and relationship between the antioxidant activity molecular supramolecular structure fullerene C 60 some its N -monosubstituted amino acid derivatives have been studied. introduction an substituent in molecule led to increase antiradical free radical oxidation a water-soluble target (fluorescein). mechanism is not associated with hyd...

Abstract. The rate at which freshly formed secondary aerosol particles grow is an important factor in determining their climate impacts. growth of atmospheric nanoparticles may be affected by particle-phase oligomerization and decomposition condensing organic molecules. We used the Model for Oligomerization Decomposition Nanoparticle Growth (MODNAG) to investigate potential significance these e...

Green tea contains numerous bioactive compounds that may provide multiple health benefits, including antioxidative, anti-inflammatory, anti-carcinogenic, anti-proliferative, anti-hypertensive, antithrombogenic and lipid-lowering effects. Most of the chemopreventive and therapeutic effects of green tea extracts have been attributed to the presence of different polyphenolic bioactives, especially...

The effective treatment of human diseases using smallmolecule and macromolecular therapeutics continues to present significant challenges to the biomedical community. In part, this stems from the physical properties of individual drug candidates, which are typically hydrophobic and poorly aqueous soluble. This necessitates the use of excipients to solubilize these compounds for delivery, which ...