We amplified by PCR and sequenced Streptococcus pneumoniae rpoB from DNA of the cardiac valve of a man who had presented with pneumococcal endocarditis 7 years earlier. Histopathologically, the valve did not show evidence of endocarditis. This case raises the question of persistence of DNA without any evidence of infection.

Streptococcus pneumoniae is a primary cause of bacterial infection in humans. Here, we present the complete genome sequence of S. pneumoniae strain A026, which is a multidrug-resistant strain isolated from cerebrospinal fluid.

We have used HiSeq 2000 technology to generate a draft genome sequence of Streptococcus pneumoniae strain A66. This is a common study strain used in investigations of pneumococcal bacterium-host interactions and was used in the seminal genetic studies of Avery et al.

A new method for the serological grouping of streptococci by coagglutination with specific antibodies absorbed to protein A-containing staphylococci has been assessed. A total of 242 strains of streptococci, including beta-haemolytic streptococci of groups A, B, C, F, and G, Streptococcus pneumoniae and Strep. faecalis were studied. All streptococci of groups A, B, C, and G, groupable by standa...

background community acquired pneumonia (cap) is a common health concern and the main mortality factor worldwide. nowadays, legionella pneumophila is one of the most common microorganisms responsible for cap. we designed this study to investigate the antigen test as a useful, simple and rapid test for early diagnosis of legionella pneumophila. materials and methods we enrolled 118 patients (32 ...

To investigate the role of putative virulence factors of Streptococcus pyogenes (group A streptococcus; GAS) in causing disease, we introduced specific mutations in GAS strain B514, a natural mouse pathogen, and tested the mutant strains in two models of infection. To study late stages of disease, we used our previously described mouse model (C3HeB/FeJ mice) in which pneumonia and systemic spre...

Virtual Screening and Molecular Docking analysis for Tabernaemontana divaricata derived 66 Law Molecular Weight Compounds (LMW) was conducted and to identified and predicted novel molecules as a inhibitor of Streptococcus pneumonia. The investigation has revealed several compounds with optimum binding towards Penicillin-binding proteins, Sialidases, Aspartate betasemialdehide dehydrogenase cell...

The intrabronchial insufflation of a non-virulent pneumococcus causes, like the insufflation of a virulent pneumococcus, the development of an exudate in the lungs which, in general, leaves the framework unaffected, and the lesion presents the gross appearance of a lobar pneumonia. It differs, however, materially from the pneumonia produced by virulent pneumococci in the important points that t...