BACKGROUND: Phenobarbital is one of the most commonly used drugs to treat epilepsy and other seizure disorders in dogs and cats. Hepatotoxicity following phenobarbital administration is dose-dependent. OBJECTIVES: The present study aimed to evaluate the protective action of silymarin on phenobarbital-in- duced hepatotoxicity in cats. METHODS...

Ayurveda, the Indian art of holistic medicine describes fasting in terms of Upavasa and considers it as one among the depletion therapies.   Besides the extensive explanations on the preventive purports of fasting, the classics have explicitly explained and exemplified the therapeutic importance of fasting while treating different diseases and dealing with different stages of the diseases. Feve...

Cancer stem cells (CSCs) have been identified as rare cellular populations in many cancers, including leukemia and solid tumors. This minor subpopulation of cancerous cells is immortal tumor-initiating cells which thought to be responsible for cancer initiation, progression, metastasis, recurrence and drug/radiation resistance. Low proliferative rate, high self-renewing capacity, differentiatio...

introduction: the city can pay attention to citizen' needes is a healthy city. today disabled people are part of developing countries population due to war and natural disasters. and disabled people increase in developing countries. in the national development plans don’t tendency to them. research on disability has generally been undertaken by educated, white researchers from developed co...

among the lesions induced by chemotherapeutic drugs, dna double-strand breaks (dsb) are considered the most serious ones that can result in cell death, if it is not properly repaired. homologous recombination (hr) pathway is the main system for dsb repair and xrcc3 has a key role in this pathway. protein activity can be affected by the xrcc3 polymorphism. thus, in this study, the association be...

objective: leishmaniasis is one of the six most common parasitic infections in tropical regions. there are different therapeutic modalities. however therapeutic resistance is developed and resulted in numerous problems. so evaluation of other therapeutic modalities is performed extensively. we compared the therapeutic response of cutaneous leishmaniasis with glucantime and garlic extract and it...

cancer stem cells (cscs) have been identified as rare cellular populations in many cancers, including leukemia and solid tumors. this minor subpopulation of cancerous cells is immortal tumor-initiating cells which thought to be responsible for cancer initiation, progression, metastasis, recurrence and drug/radiation resistance. low proliferative rate, high self-renewing capacity, differentiatio...