The problem of antimicrobial resistance has led some infectious disease experts and their professional societies to propose the use of transferable intellectual property rights (wildcard patents) and patent term extensions as methods to encourage antimicrobial research and development. We evaluate recent approvals of new antimicrobial classes and find that the number of new introductions is hig...

In this work, the antimicrobial property of nanocomposite prepared by loading of silver nanoparticle onto activated carbon (AgNP-AC) was studied. The silver nanoparticles were synthesized biologically from the culture Enterobacter aerogenes and loaded onto the activated carbon. The nanoparticle and nanocomposite were characterized by UV-vis, scanning electron microscopy and X-ray diffraction st...

Plant defensive metabolite Alkaloid were screened for analyzing their antimicrobial property. The present study quantified the alkaloids present in selected members of tribe Amarantheae. Maximum percentage of alkaloids are shown by Amaranthus tricolor L., Aamaranthus viridis L. and Amaranthus caudatus L. (88.8%) and the least were shown by Amaranthus spinosus L. and Amaranthus dubius Mart. (5.8...

objectives: this study sought to assess the effect of curcumin nanoparticles (curcnps) on antimicrobial property and shear bond strength (sbs) of orthodontic composite to bovine enamel. materials and methods: in this in vitro, experimental study, 1%, 5% and 10% curcnps were added to transbond xt composite. stainless steel brackets were bonded to 48 sound bovine incisors in four groups (n=12) us...

In general antibiotics interact cooperatively with host defences, weakening and decreasing the virulence of microbial pathogens, thereby increasing vulnerability to phagocytosis and eradication by the intrinsic antimicrobial systems of the host. Antibiotics, however, also interact with host defences by several other mechanisms, some harmful, others beneficial. Harmful activities include exacerb...

Rhamnolipid biosurfactants produced mainly by Pseudomonas sp. had been reported to possess a wide range of potential industrial application. These biosurfactants are produced as monorhamnolipid (MRL) and di-rhamnolipid (DRL) congeners. The present study deals with rhamnolipid biosurfactants produced by three bacterial isolates from crude oil. Biosurfactants produced by one of the strains (named...

OBJECTIVE In an attempt to find a better treatment for bacterial infections and burn wounds, various semisolid formulations containing 5% w/w of norfloxacin were prepared and evaluated for physicochemical parameters, in vitro drug release through cellophane membrane, antimicrobial activity, and burn wound healing properties. The prepared formulations were compared with silver sulfadiazine 1% cr...

Our previous studies demonstrated that among phenothiazines several derivatives could be found showing strong antiproliferative actions and the property of inhibiting inducible tumor necrosis factor alpha (TNF a) production in human blood cultures. The aim of this investigation was to determine potential antimicrobial actions of forty four new phenothiazine derivatives with the quinobenzothiazi...

In this work the chemical composition and antimicrobial activity of Pelargonium roseum leaves essential oil that grown in southwest of Iran were determined. The hydrodistilled volatile components were identified by GC/MS analysis. A total of 33 components have been identified in the oil, representing 99.38% of the total oil and citronellol (44.63%), citronellyl formate (14.22%), isomenthon (6.3...