نتایج جستجو برای: cdna synthesis and real
تعداد نتایج: 16967463 فیلتر نتایج به سال:
Background and Aims: Lung cancer is one of the most common malignancies worldwide that despite the recent progress, its existing treatments have not sufficient efficiency, and scientists are always trying to find complementary therapies. Medicinal plants, such as sour tea, have attracted lots of attention due to their abundant antioxidant compounds. In the present study, in addition to assessin...
Background: With the increasing concern for health and nutrition, dietary fat has attracted considerable attention. The composition of fatty acids in the diet is important because they are associated with major diseases including cancers, diabetes, and cardiovascular disease. The fatty acid synthase (FASN) and stearoyl-CoA desaturase (delta-9-desaturase) (SCD) genes affect fatty acid compositio...
Abstract The development of insects is critically affected by temperature, which therefore plays an important role in the control stored grain pests. Extreme temperature stress conditions lead to biological responses mites, such as synthesis heat shock proteins. Tyrophagus putrescentiae ( Tp ) a pest mite that has negative effects on both economy and health. Since T. population dynamics are str...
Troxerutin, a derivative of the natural bioflavonoid rutin, has important biological effects, including immunostimulatory activity. This study aimed to evaluate the effects of dietary troxerutin supplement on histology and mRNA expression of the genes encoding lysozyme and tumor necrosis factor-α in goldfish, Carassius auratus skin. Fish fingerlings with mean initial weights of 2.74 ± 0.08 g we...
Evaluation of ATG7 and LC3 Autophagy Genes Expression in Newly Diagnosed AML patients Background and aim: Autophagy, known as cell death type II, is a housekeeping pathway that currently has been worked on in matters of tumorigenesis and leukemogenesis. Therefore, in this study expression levels of ATG7 and LC3 as two key genes are targeted in AML patients. Material and method: This...
Aim and Background: Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder with cytogenetic characterization of the abnormal Philadelphia chromosome. This chromosome results from a reciprocal translocation between chromosomes 9 and 22. This is an important signaling pathway in the process of cancer cell proliferation and apoptosis, as well as the pathogenesis of TGF-β disease, i...
Evaluation of ATG7 and LC3 Autophagy Genes Expression in Newly Diagnosed AML patients Background and aim: Autophagy, known as cell death type II, is a housekeeping pathway that currently has been worked on in matters of tumorigenesis and leukemogenesis. Therefore, in this study expression levels of ATG7 and LC3 as two key genes are targeted in AML patients. Material and method: This...
Head and neck squamous cell carcinoma (HNSCC) represents a large majority of cancers arising from the head and neck, especially the oral cavity. Despite advances in therapy, the five-year survival rate remains low due to the number of patients presenting advanced stages of the disease. The role of epithelial-mesenchymal transition (EMT) in tumorigenesis in HNSCC remains unexplored. The current ...
Background: Rheumatoid arthritis (RA) is an autoimmune disease caused by accumulation of numerous inflammatory cells in the joints and secretion of various cytokines leading to cartilage and bone damage. IL-17 and IL-23 are inflammatory cytokines that their definite role has not been clearly distinguished in RA pathogenesis. Therefore, this study aimed to investigate the expression and associat...
Background and purpose: T-cell acute lymphoblastic leukemia (T-ALL) is a type of blood malignancy caused by changes in the precursors of T lymphocyte cells. The PTEN gene is one of the most common tumor suppressor genes that mutates in most human cancers, including T-ALL. Therefore, it is important to identify miRNAs that target the PTEN gene in T-ALL. For this purpose, in the present study, mi...
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