Human peripheral blood mononuclear cells in adherent cultures have been shown to synthesise and secrete collagenase. In the present study we have examined the modulation of collagenase production in these cultures by several antirheumatic agents. Incubation of monocytes in serum free medium with sodium aurothiomalate in concentrations varying from 7.7 X 10(-7) to 7.7 X 10(-3) mol/l resulted in ...

Objective: In the present scenario, biogenic production of gold nanoparticles (AuNPs) and silver nanoparticles (AgNPs) has evoked considerable interest in terms of their diverse biomedical applications because of their extremely small size and large surface to volume ratio. Hence, the aims of the current study were to use the plant extract for the biosynthesis of AgNPs and AuNPs and to evaluate...

AuNPs have been in the focal point of researchers’ attention for years because of high biocompatibility and adjustable surface plasmon resonance (SPR) [1]. In the recent years, many studies have been performed in producing AuNPs via green synthesis techniques, i.e. use of plants for producing AuNPs [2]. Green synthesis methods are eco-friendly and increase the biocompatibility of AuNPs [3]. A f...

Objective(s): Drug delivery is an engineering technology to control the release and delivery of therapeutic agents to target organs, tissues, and cells. Metallic nanoparticles, such as gold nanoparticles (AuNPs) have exceptional properties which enable efficient drug transport into different cell types with reduced side effects and cytotoxicity to other tissues.Materials and Methods: AuNPs were...

BACKGROUND Nanobiotechnology applies the capabilities of biological systems in generating a variety of nano-sized structures. Plants, algae, fungi and bacteria are some systems mediating such reactions. In fungi, the synthesis of melanin is an important strategy for cell-survival under metal-stressed conditions. Yarrowia lipolytica, the biotechnologically significant yeast also produces melanin...