Severe dengue is characterised by thrombocytopenia, plasma leakage and bleeding. Platelets are important for preservation of endothelial integrity. We hypothesised that platelet activation with secondary platelet dysfunction contribute to plasma leakage. In adult Indonesian patients with acute dengue, we measured platelet activation status and the response to the platelet agonist TRAP using flo...

background: recurrent pregnancy loss (rpl) is defined as two or more miscarriages before the 20 th week of gestation and its etiology is unknown in 50% of the cases. interleukin 6 is an immune mediator, plays a regulatory role in embryo implantation and placental development. objective: the purpose was to assess the association between il-6 -634c/g polymorphism and, susceptibility to idiopathic...

The mechanisms by which Shaoyao-Gancao decoction (SGD) inhibits the production of inflammatory cytokines in serum and brain tissue after cerebral ischemia-reperfusion (CI-RP) in rats were investigated. A right middle cerebral artery occlusion was used to induce CI-RP after which the rats were divided into model (n = 39), SGD (n = 28), clopidogrel (n = 25) and sham operated (n = 34) groups. The ...

in order to study the effect of different concentrations of salicylic acid in two commercial apricotcultivars of shahrood namely ‘shahrood 41’ and ‘jaffari’, under cold stress, a factorial experiment wasconducted in a randomized complete block design with three replications in 2012 at the agriculturalresearch center of shahrood city. the test had four factors including: sa with three levels (0....

BACKGROUND Interleukin-17 (IL-17) is a family of emerged pro-inflammatory cytokines. The IL-17A and IL-17F are two important members of IL-17 family. Previous studies have shown that the functional IL-17A G-197A and IL-17F 7488T/C polymorphisms may contribute to susceptibility to cancer but the results were inconclusive. This meta-analysis was performed to determine the exact association betwee...

this experiment was carried out as factorial based on randomized complete block design with four replications in 2011-2012 growing season. the experimental factors were selenium in four levels 0, 6, 12 and 18 g ha-1 and salicylic acid in three levels 0, 100 and 200 mg l-1. results showed that foliar application of selenium at rate of 12 and 18 g ha-1 decreased ion leakage by 11.6 and 18.8% comp...

Melatonin is a new plant hormone that plays an important role in stress tolerance. For investigation the effect of exogenous application of melatonin on salt tolerance in rosemary (Rosmarinus officinalis L.), a factorial experiment was conducted in a completely randomized design with three replications. The first factor was melatonin (50, 100 µM) and the second factor was salinity stress (6, 9,...