The ability to control protein-protein interactions (PPIs) for therapeutic purposes is attractive since many processes in cells involve such interactions. Recent successes in the discovery of small molecules that target protein-protein interactions for drug development have shown that targeting these interactions is indeed feasible. In the present review the use of computer-aided drug design (C...

This volume details state-of-the- art methods on computer-aided antibody design. Chapters guide readers through information sequences.

Initially, the design of new drugs was based on the prototypical molecule, usually a natural product and making structural modifications. For designing of new drugs the understanding of the etiology of the disease and the structure of the receptor where the ligand (drug) will bind is very much important. Now a day, there is increasing computational power coupled with applicable software, has le...

Computer-aided process planning (CAPP) is an essential component in linking computer-aided design (CAD) and computer-aided manufacturing (CAM). Operation sequencing in CAPP is an essential activity. Each sequence of production operations which is produced in a process plan cannot be the best possible sequence every time in a changing production environment. As the complexity of the product incr...