The effects of oxandrolone or biosynthetic human growth hormone (r-hGH) on the growth of 26 boys with constitutional delay of growth and puberty were studied. Both regimens increased growth rate twofold, oxandrolone to a greater extent than r-hGH. We conclude that oxandrolone is a more effective method of increasing growth rate in such children.

survey of influencial factors on age of puberty of high   school students in neyshabour     m. vafaei [1] , m. sadat hoseini [2] , r. froutan [3]     abstract:   introduction: puberty is a period that the children's body undergo kind of change so children change to puberty.   almost the average age for boy puberty is 12 years old. psychologists said: puberty is eventful obliging for a good...

BACKGROUND: Children with primary hypothyroidism usually presents delay in linear growth and pubertal development, but rare instances they can present precocious puberty. In 1960, presentation of puberty was first reported labelled as Van Wyk Grumbach syndrome (VWGS). We report a case VWGS six years old girl. CASE DESCRIPTION: A girl presented accompanied by short stature delayed bone age due t...

Phytoestrogens, phthalates, and phenols are estrogen-disrupting chemicals that have a pronounced effect at puberty. They are exogenous chemicals that are either plant-derived or man-made, and can alter the functions of the endocrine system and cause various health defects by interfering with the synthesis, metabolism, binding, or cellular responses of natural estrogens. Phytoestrogens, phthalat...

The social environment can alter pubertal timing through neuroendocrine mechanisms that are not fully understood; it is thought that stress hormones (e.g., glucocorticoids or corticotropin-releasing hormone) influence the hypothalamic-pituitary-gonadal axis to inhibit puberty. Here, we use the eusocial naked mole-rat, a unique species in which social interactions in a colony (i.e. dominance of ...

BIOLOGIC CHANGES LEADING TO SLEEP CHANGES About the time that puberty starts, adolescents develop a 2-hour sleep-wake “phase delay.” This means that if your child usually went to bed at 8 PM and woke up at 6 AM, then during adolescence he or she may feel more awake in the evening so that he or she does not feel like he or she has to go to bed until around 10 PM. Since most adolescents still hav...

Internationally adopted children appear to reach puberty at a relatively young age and to have a high risk of early puberty including very early or precocious puberty (PP), that is, pubertal development at,8 years of age for girls and at ,9 years of age for boys. However, there can be uncertainty over the chronological age of adopted children, raising the possibility that the seemingly elevated...

OBJECTIVE The association between type 1 diabetes mellitus (T1D) and dyslipidemia (DLP) increases the risk of cardiovascular disease (CVD). The aim of this study was to evaluate the presence of dyslipidemia in young T1D patients. MATERIALS AND METHODS The study design was cross-sectional and descriptive. We reviewed medical records of T1D patients followed at an endocrinology service, from 19...