hypothalamic hamartoma (hh) is a rare intracranial lesion that usually presents with classic triad of central precocious puberty, gelastic epilepsy, and developmental delay. herein, a 14-year old boy is presented in whom the diagnosis of hh was made by magnetic resonance imaging. while he did not have any complain of precocious puberty, he surprisingly suffered from delay in puberty. the defini...

Hypothalamic hamartoma (HH) is a rare intracranial lesion that usually presents with classic triad of central precocious puberty, gelastic epilepsy, and developmental delay. Herein, a 14-year old boy is presented in whom the diagnosis of HH was made by magnetic resonance imaging. While he did not have any complain of precocious puberty, he surprisingly suffered from delay in puberty. The defini...

1. Define the ages at which puberty is considered delayed in boys and girls. 2. Discuss the typical presentation and natural history of constitutional delayed puberty. 3. Compare the differential diagnosis of delayed puberty for causes other than constitutional delay in girls versus boys. 4. Recognize the psychological consequences of pubertal delay. 5. Describe the evaluation and treatment of ...

Constitutional delay of growth and puberty (CDGP) is not a disease but a common condition in which puberty and its associated growth spurt occur at an age which is near the extreme of the normal range. Growth at puberty is intimately related to the stage of pubertal development and this is why, quite appropriately, both growth and puberty are implicit in the name, although it could be argued th...

Height and weight were measured every six months in a long term prospective study of 66 children with chronic perennial asthma for a mean 13.1 years. There was no evidence of growth retardation on entry into the study. Growth developed along normal lines in all 66 children until about 10 years, and in 35 of these children growth continued along normal lines throughout the whole period of follow...