The dynamic changes in the temporal appearance and quantity of a new class of influenza virus, noninfectious cell-killing particles (niCKP), were compared to defective interfering particles (DIP). After a single high-multiplicity passage in MDCK cells of an egg-derived stock that lacked detectable niCKP or DIP, both classes of particles appeared in large numbers (>5 x 10(8)/ml), and the plaque-...

In an effort to combine the benefits of fibrinolytics, such as staphylokinase, with those of thrombin inhibitors for the prevention of vessel reocclusion after vascular injury, we have produced several chimeric proteins with plasminogen-activating and thrombin-inhibiting properties. Fusion proteins were constructed consisting of the modules staphylokinase (Sak), the factor Xa cleavage site, and...

During a research project to improve the performance and operation of shower dips, a series of measurements of the diazinon based dip-wash concentrations were taken. These measurements, although not replicated, indicated that the concentrations were falling to levels which were considered to be too low. As a result a replicated trial was conducted on the same shower dip, modified as per the fin...

Information can propagate among Online Social Network (OSN) users at a high speed, which makes the OSNs become important platforms for viral marketing. Although the viral marketing related problems in OSNs have been extensively studied in the past decade, the existing works all assume known propagation rates and are not able to solve the scenario when the rates may dynamically increase for popu...

REASONS FOR PERFORMING STUDY Increased joint pressure has been implicated in the progression of osteoarthritis. HYPOTHESIS That intra-articular pressure in the distal interphalangeal joint (DIP) is significantly higher in legs loaded with heel up (HU), low heel (TU), lateral side up (LU) and medial side up (MU) imbalance compared to the balanced position. METHODS Twelve elbow down limbs wer...

The purpose of this study was to determine the relationship between ventricular excitability and the extrastimulus (S2) coupling interval in early diastole in humans. The influence of the electrode configuration during bipolar stimulation was examined. Ventricular strength-interval curves were constructed using an eight beat drive train at a cycle length of 600 msec, 2-msec decrements in the S2...

The initial decrease in BOLD signal at stimulus onset (i.e., the initial dip) has generated a great deal of interest because of its potential for providing more spatially specific mapping. Despite a number of experimental fMRI studies demonstrating its existence in the visual cortex, the initial dip has not been reported in other areas. The present work examined the initial dip in the motor are...

Most Thermococcales accumulate di-myo-inositol-phosphate (DIP) as an organic solute as a response to heat stress. We have studied the accumulation of this osmolyte in the high-hydrostatic pressure adapted hyperthermophile Thermococcus barophilus. We found no accumulation of DIP under any of the stress conditions tested, although this archaeon harbors the 3 DIP synthesis genes. Lack of synthesis...

Addictive drug use or prescribed medicine abuse can cause psychosis. Some representative symptoms frequently elicited by patients with psychosis are hallucination, anhedonia, and disrupted executive functions. These psychoses are categorized into three classifications of symptoms: positive, negative, and cognitive. The symptoms of DIP are not different from the symptoms of schizophrenia, and it...