This paper presents an efficient optimization procedure to find the optimal shapes of double curvature  arch  dams  considering  fluid–structure  interaction  subject  to  earthquake  loading. The optimization is carried out using a combination of the magnetic charged system search, big bang-big crunch algorithm and artificial neural network methods. Performing the finite element  analysis  dur...

This chapter provides an overview of the current computational methods for PPI network cleansing. The authors first present the issue of identifying reliable PPIs from noisy and incomplete experimental data. Next, they address the questions of which are the expected results of the different experimental studies, of what can be defined as true interactions, of which kind of data are to be integr...

Proteins are some of the building blocks of organisms. They usually perform their functions by interacting with each other and forming protein complexes. A protein-protein interaction network is a graph that consists of proteins as vertices and their interactions as edges. Protein-protein interaction network alignment is very important in identifying protein complexes and predicting protein fun...

Protein-protein interactions (PPI) play a key role in determining the outcome of most cellular processes. Correctly identifying and characterizing protein interactions and the networks they comprise is critical for understanding the molecular mechanisms within the cell. Large-scale biological experimental methods can directly and systematically detect the set of interacting proteins within an o...