Nitroaromatic compounds, ArNO2 have widespread actual or potential use in medicine and cancer therapy. There is direct proof that free-radical metabolites are involved in many applications, and an appreciation of the conceptual basis for their therapeutic differential; however, an understanding of the detailed mechanisms involved is lacking. Redox properties control most biological responses of...

In this paper, two novel alkali clearable disperse dyes were synthesized. 4-flourosulfonyl aniline and 2-nitro-4-flourosulfonyl aniline were utilized as the diazo components and 2- naphthol as the coupling component. The DSC, FTIR, 1HNMR and UV-Vis analyses were used to characterize the synthesized intermediates and dyes. The synthesized dyes were used to dye polyester fibers and their dyeing p...

The metal-free reduction of nitro compounds to amines mediated by trichlorosilane was successfully performed for the first time under continuous-flow conditions. Aromatic as well as aliphatic nitro derivatives were converted to the corresponding primary amines in high yields and very short reaction times with no need for purification. The methodology was also extended to the synthesis of two sy...

Yellow crystals of the title compound 3-amino-4-nitro-benzyl acetate, C9H10N2O4, were isolated from the reaction of acetic anhydride with (5-amino-2-nitro-phen-yl)methanol, prepared from reduction of commerically available 5-amino-2-nitro-benzoic acid with borane-THF. The mol-ecule is essentially planar (r.m.s. deviation = 0.028 Å). The mol-ecules are linked by inter-molecular N-H⋯O hydrogen-bo...

We have examined the quenching of pyrochlorophyll fluorescence by a series of substituted nitrobenzenes in ethanol-pyridine solution and the effect of fluorescence quenching on the quantum yield of sensitized photoreduction of three of the nitro compounds by hydrazobenzene. All nitro compounds examined are at least moderately good quenchers of fluorescence. There is a good correlation between t...

It has previously been reported from this laboratory (Saz and Slie, 1954a) that chlortetracycline ("aureomycin") in concentrations of 1 to 100 ,ug per ml inhibited an enzyme complex from Escherichia coli strain E-26 mediating the reduction of chloramphenicol and other aromatic nitro compounds to the corresponding arylamines. The cofactor requirements for this organic nitro reductase were found ...