to investigate the effects of the two-pore-domain potassium (k2p) channel task-3 in a syngeneic murine model for malignant glioma. malignant or high-grade glioma (who grade iii and iv) are the most common and most aggressive primary brain tumors in adults. despite aggressive multimodal therapy, the outcome of patients with malignant glioma remains poor. however, recent phase i and ii trials hav...

background: hypertension is one of the major chronic disorders. hypertensive patients have various disease-related experiences, based on personal and social characteristics, life style and other effective factors. nurses face different situations during their activities process and presentation of these experiences obtained during working with patients can help them to improve the clinical acti...

objective: non-compliance is one of the major problems in treatment of patients with schizophrenia. it is also the most significant risk factor for relapse and re-hospitalization. previous studies showed that 25-70% of all patients with schizophrenia have negative attitudes to drugs. therefore, the present study aimed to identify the relationship between drug attitude and discharge and the rate...

background: the aim of the present study was to develop a scoring system for predicting 1-year major adverse cardiac events (mace), including mortality, target vessel or target lesion revascularization, coronary artery bypass graft surgery, and non-fatal myocardial infarction after percutaneous coronary intervention (pci). methods: the data were extracted from a single center pci registry. the ...

introduction: myofascial pain dysfunction syndrome (mpds) is one of the most important causes of the orofacial pain. the main purpose of this study was to evaluate 40 related variables in this regard. materials and methods: thirty nine patients with mpds were evaluated in this study. different factors including age, gender, occupation, marital status, sensitivity of masticatory muscles, maximum...

background : due to specific conditions in hospitals such as accumulation, existence of disable persons and patients, different and complex equipment, chemical and infectious substances, flammable materials and ionized radiations, safety precautions is essential to prevent the occurrence of incidents such as fire, electric shock hazard and exposure to excessive levels in hospitals. this was the...

responding to ruth mcdonald’s editorial on the rise of leadership and leadership development programmes in healthcare, this paper offers three arguments. firstly, care is needed in evaluating impact of leadership development, since achievement of organisational goals is not necessarily an appropriate measure of good leadership. secondly, the proliferation of styles of leadership might be unders...

pierre-gerlier forest has put forward the case that we are on the brink of a revolution in health policy that will be the result of the interplay of five factors. i would not challenge any of them but would emphasize the need to address socio-economic health inequalities, which have the potential to become a major cost driver in a time of growing economic inequality. to dr. forest’s list, i wou...

the doctor-patient relationship (dpr) is a complex concept in the medical sociology in which patients voluntarily approach a doctor and thus become a part of a contract in which they tends to abide with the doctor’s guidance. globally, the dpr has changed drastically over the years owing to the commercialization and privatization of the health sector. furthermore, the dynamics of the dpr has sh...