We use the sample covariation to develop asymptotic tests for independence for data in the normal domain of attraction of a stable law. The tests can be used for finite or infinite variance processes. In a simulation study we compare the finite sample performance of the proposed tests to the Portmanteau test commonly used in time series modeling. The null convergence of the test statistics to t...

Melanocortin-4-receptor (MC4R)-expressing neurons modulate food intake and preference in rodents but their role in human food preference is unknown. Here we show that compared with lean and weight-matched controls, MC4R deficient individuals exhibited a markedly increased preference for high fat, but a significantly reduced preference for high sucrose food. These effects mirror those in Mc4r nu...

The unified neutral theory of biodiversity and biogeography is increasingly accepted as an informative null model of community composition and dynamics. It has successfully produced macro-ecological patterns such as species-area relationships and species abundance distributions. However, the models employed make many unrealistic auxiliary assumptions. For example, the popular spatially implicit...

Following the formalism used for the development of the knowledge-based scoring function DrugScore, new distance-dependent pair potentials are obtained from nonbonded interactions in small organic molecule crystal packings. Compared to potentials derived from protein-ligand complexes, the better resolved small molecule structures provide relevant contact data in a more balanced distribution of ...

frying oils showed an increase in peroxide value (pv) at the initial stages of the frying process followed by a decrease, and there was no correlation between pv and total polar compounds (tpc) in the same set of frying oils. all the frying oils had pvs lower than 4.42 meq o2 kg-1 oil during the frying process and, consequently, none of them was above the limit of 10 meq o2 kg-1 oil for edible ...