to study inheritance of resistance to septoria tritici blotch in wheat, the generation mean analysis method was used. so six generations (p1, p2, f1, f2, bc1 and bc2) were planted under completely randomized design with three replications in greenhouse. seedlings were inoculated at the second-leaf stage with an isolate of septoria tritici and necrosis and picnidia density and area under disease...

Diallel analysis assumes that the genetic interactions contributing to trait variation can be adequately captured by GCA and SCA effects. However, in reality, more complex, involving higher-order epistatic interactions, pleiotropy, other factors are not accounted for traditional diallel analysis, this purpose, studies were conducted study combinatorial ability of wheat varieties widely planted ...

While animal breeders largely focus on improvement using additive genetic variance, inbreeding and asexual reproduction allow plant breeders to at least partially exploit nonadditive genetic variance as well. We briefly review various approaches used by breeders to exploit dominance and epistatic variance, discuss their constraints and limitations, and examine what (if anything) can be done to ...

To date, genome-wide association studies (GWAS) permit a comprehensive scan of the genome in an unbiased manner, with high sensitivity, and thereby have the potential to identify candidate genes for the prevalence or development of multifactorial diseases such as bronchial asthma. However, most studies have only managed to explain a small additional percentage of hereditability estimates, and o...

The construction of abstractions is essential for reducing large or innnite state systems to small or nite state systems. Boolean abstractions, where boolean variables replace concrete predicates, are an important class that subsume several abstraction schemes. We show how boolean abstractions can be constructed simply, eeciently, and precisely for innnite state systems while preserving propert...

Understanding the molecular basis of phenotypic diversity is a critical challenge in biology, yet we know little about the mechanistic effects of different mutations and epistatic relationships among loci that contribute to complex traits. Pigmentation genetics offers a powerful model for identifying mutations underlying diversity and for determining how additional complexity emerges from inter...

The detection of epistatic interactive effects of multiple genetic variants on the susceptibility of human complex diseases is a great challenge in genome-wide association studies (GWAS). Although methods have been proposed to identify such interactions, the lack of an explicit definition of epistatic effects, together with computational difficulties, makes the development of new methods indisp...