نتایج جستجو برای: گیرنده nogo

تعداد نتایج: 7514  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس 1389

چکیده هدف: ms شایعترین بیماری التهاب مزمن و دمیلینه کننده در سیستم عصبی مرکزی انسان است. ظرفیت ترمیم در این بیماری وجود دارد اما کافی نیست. شناسایی منبعی از سلول های بنیادی درون زاد مغز با ظرفیت بالای تکثیر، مهاجرت و تمایز به اولیگودندروسیت های مولد میلین، به توسعه استراتژی های جدید برای ترمیم کمک شایانی نموده است. این nscs های بطن های جانبی و بطن سوم ، تحت تاثیر سیگنال های محیطی توانایی تکثیر...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس 1390

هدف: ام اس بیماری التهابی دمیلینه کننده مزمن در سیستم عصبی مرکزی است. افزایش مشارکت سلولهای بنیادی عصبی در ترمیم اندوژن آسیبهای میلینی یکی از مهمترین استراتژیها برای درمانهای نوین این بیماری است. در مطا لعه حاضر رفتار سلولهای بنیادی عصبی در مدل eae (مدل حیوانی ارزیابی شاخصهای التهابی و رفتاری بیماری ام اس) بررسی می شود. nogo66 (بخش خارج سلولی nogo با 66 اسید آمینه) به رسپتور nogo (ngr) متصل شده...

Journal: :Frontiers in Psychology 2021

Sequential congruency effects are observed in interference tasks, which reaction times (RTs) shorter for congruent stimuli preceded by (cC) than incongruent (iC), and RTs longer (cI) (iI). These interpreted as resulting from triggering attentional control the next trial, reduces cognitive control. This study aimed to examine sequential on event-related potential (ERP) components Go- Nogo-stimul...

Journal: :Journal of Molecular Histology 2021

Nogo-A protein consists of two main extracellular domains: Nogo-66 (rat amino acid [aa] 1019–1083) and Nogo-A-?20 (extracellular, active 180 region), which serve as strong inhibitors axon regeneration in the adult CNS (Central Nervous System). Although receptors S1PR2 HSPGs have been identified binding proteins, it remains at present elusive whether other directly interacting with exist, decrea...

Ardalan Aarabi, Fabrice Wallois, Masoud Nosratabadi, Mohammad Ali Nazari, Patrick Berquin,

ABSTRACT Introduction: Several differences in the P300 component are observed when responses must be executed or inhibited in the Go/Nogo task. However, few studies were established by using well-controlled task with respect to the preparatory processing and stimulus probability. In the present study, we examined the peak amplitude and latency of Go-P300 (P300 evoked by visual Go stimuli) and N...

Journal: :basic and clinical neuroscience 0
mohammad ali nazari fabrice wallois ardalan aarabi masoud nosratabadi patrick berquin

abstract introduction: several differences in the p300 component are observed when responses must be executed or inhibited in the go/nogo task. however, few studies were established by using well-controlled task with respect to the preparatory processing and stimulus probability. in the present study, we examined the peak amplitude and latency of go-p300 (p300 evoked by visual go stimuli) and n...

Journal: :Behavioural Brain Research 2021

Alcohol use disorder (AUD) is characterized by both impaired inhibitory control and heightened cue reactivity, including enhanced craving drinking urges in response to alcohol-related stimuli. The interaction between these two mechanisms thought be crucial the maintenance of addiction relapse. present study used a newly developed Go/NoGo-task investigate how exposure cues affects neural process...

تربالی, سپیده, خضری, شیوا, رحمانی, فاطمه, صمدی, ﺳﭙﻴﺪه,

Background and purpose: Optic neuritis is one of the appearances of Multiple Sclerosis (MS).  Progesterone has a protective effect in central nervous system, so, in this study we aimed at investigating the effect of progesterone on myelin repair of the optic chiasm in male rats by studying the genes expression of Olig 2 (marker of oligodendrocyte precursor cells), GFAP (marker of astrocyte...

2015
Koya Yamashiro Daisuke Sato Hideaki Onishi Kazuhiro Sugawara Sho Nakazawa Hirofumi Shimojo Kosuke Akatsuka Hiroki Nakata Atsuo Maruyama Wing-ho Yung

Athletic training is known to induce neuroplastic alterations in specific somatosensory circuits, which are reflected by changes in somatosensory evoked potentials and event-related potentials. The aim of this study was to clarify whether specific athletic training also affects somatosensory Nogo potentials related to the inhibition of movements. The Nogo potentials were recorded at nine cortic...

Journal: :Journal of immunology 2004
Paulo Fontoura Peggy P Ho Jason DeVoss Binhai Zheng Byung J Lee Brian A Kidd Hideki Garren Raymond A Sobel William H Robinson Marc Tessier-Lavigne Lawrence Steinman

Nogo-66, the extracellular 66 aa loop of the Nogo-A protein found in CNS myelin, interacts with the Nogo receptor and has been proposed to mediate inhibition of axonal regrowth. It has been shown that immunization with Nogo-A promotes recovery in animal models of spinal cord injury through induction of Ab production. In this report, studies were performed to characterize the immune response to ...

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