نتایج جستجو برای: 1 perforin proviral load

تعداد نتایج: 2872665  

2001
Yoshihisa Yamano Masahiro Nagai Meghan Brennan Carlos A. Mora Samantha S Soldan Utano Tomaru Norihiro Takenouchi Shuji Izumo Mitsuhiro Osame Steven Jacobson

To investigate the role of viral expression in individuals infected with human T-cell lymphotropic virus type 1 (HTLV-1), a real-time quantitative reverse transcription-polymerase chain reaction (RT-PCR) of HTLV-1 tax messenger RNA (mRNA) using ABI Prism 7700 Sequence Detection System was developed. Using this system, the HTLV-1 tax mRNA load was compared with HTLV-1 proviral DNA load, HTLV-1 T...

Journal: :Arquivos de neuro-psiquiatria 2012
Davi Tanajura Costa André Luiz Muniz Alves dos Santos Néviton Matos de Castro Isadora Cristina de Siqueira Edgar Marcelino de Carvalho Filho Marshall Jay Glesby

OBJECTIVE To compare neurological symptoms and signs in HTLV-1 asymptomatic carriers and HTLV-1 patients with overactive bladder (OB) syndrome. METHODS We studied 102 HTLV-1 positive individuals without HAM/TSP (HTLV-1 associated myelopathy/tropical spastic paraparesis) divided into two groups according to the presence or absence of OB syndrome. Clinical interview, neurological exam and provi...

Journal: :Antiviral therapy 2011
Natsumi Araya Katsunori Takahashi Tomoo Sato Tatsufumi Nakamura Chika Sawa Daisuke Hasegawa Hitoshi Ando Satoko Aratani Naoko Yagishita Ryoji Fujii Hiroshi Oka Kusuki Nishioka Toshihiro Nakajima Naoki Mori Yoshihisa Yamano

BACKGROUND Human T-lymphotropic virus type-1 (HTLV-1) is a human retrovirus that causes HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukaemia (ATL). A higher viral load in individuals with HTLV-1 infection increases their risk of developing HAM/TSP and ATL. Moreover, the high proviral load is associated with the clinical progression of HAM/TSP. Reduction...

Journal: :Blood 2002
Yoshihisa Yamano Masahiro Nagai Meghan Brennan Carlos A Mora Samantha S Soldan Utano Tomaru Norihiro Takenouchi Shuji Izumo Mitsuhiro Osame Steven Jacobson

To investigate the role of viral expression in individuals infected with human T-cell lymphotropic virus type 1 (HTLV-1), a real-time quantitative reverse transcription-polymerase chain reaction (RT-PCR) of HTLV-1 tax messenger RNA (mRNA) using ABI Prism 7700 Sequence Detection System was developed. Using this system, the HTLV-1 tax mRNA load was compared with HTLV-1 proviral DNA load, HTLV-1 T...

Journal: :iranian journal of basic medical sciences 0
rosita vakili htlv-i foundation, ghaem hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran faezeh sabet htlv-i foundation, ghaem hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran sanaz ahmadi ghezeldasht centre of pathological and medical diagnostic services, iranian academic centre for education, culture & research (acecr), mashhad branch, mashhad, iran reza boostani department of neurology, ghaem hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran houshang rafatpanah inflammation and inflammatory diseases research centre, school of medicine, mashhad university of medical sciences, mashhad, iran ali shamsian centre of pathological and medical diagnostic services, iranian academic centre for education, culture & research (acecr), mashhad branch, mashhad, iran

0

Objective(s): Coronary artery disease (CAD) is known as a life threatening disease, worldwide. In this study the role of HTLV-1 infection was evaluated on cardiac involvement in an endemic region of northeastern Iran.Materials and Methods: Serologic and molecular tests for HTLV-1 infection were carried out in subjects who had coronary an...

Journal: :Thorax 2005
S Mori A Mizoguchi M Kawabata H Fukunaga K Usuku I Maruyama M Osame

BACKGROUND A study was undertaken to investigate the pathogenesis of pulmonary involvement in human T lymphotropic virus type I (HTLV-I) carriers. METHODS The bronchoalveolar lavage (BAL) cell profile of 30 HTLV-I carriers (15 asymptomatic HTLV-I carriers (AHCs) and 15 symptomatic HTLV-I carriers (SHCs)) with chronic inflammatory diseases of respiratory tract and eight patients with HTLV-I as...

2017
Takumi HAYASHI Hirohisa MEKATA Satoshi SEKIGUCHI Yumi KIRINO Shuya MITOMA Kazuyuki HONKAWA Yoichiro HORII Junzo NORIMINE

The bovine MHC (BoLA) class II DRB3 alleles are associated with polyclonal expansion of lymphocytes caused by bovine leukemia virus (BLV) infection in cattle. To examine whether the DRB3*0902 allele, one of the resistance-associated alleles, is associated with the proviral load, we measured BLV proviral load of BLV-infected cattle and clarified their DRB3 alleles. Fifty-seven animals with DRB3*...

2005
S Mori A Mizoguchi M Kawabata H Fukunaga K Usuku I Maruyama M Osame Midori Machi

Background: A study was undertaken to investigate the pathogenesis of pulmonary involvement in human T lymphotropic virus type I (HTLV-I) carriers. Methods: The bronchoalveolar lavage (BAL) cell profile of 30 HTLV-I carriers (15 asymptomatic HTLV-I carriers (AHCs) and 15 symptomatic HTLV-I carriers (SHCs)) with chronic inflammatory diseases of respiratory tract and eight patients with HTLV-I as...

Journal: :The Journal of infectious diseases 1999
A Manns W J Miley R J Wilks O S Morgan B Hanchard G Wharfe B Cranston E Maloney S L Welles W A Blattner D Waters

The pathogenesis of human T-cell lymphotropic virus type I (HTLV-I) in adult T-cell leukemia/lymphoma (ATL) and HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP) is poorly understood. We prospectively followed up and evaluated the virologic correlates of infection in transfusion recipients after seroconversion, in asymptomatic carriers, and in ATL and HAM/TSP patients. Provira...

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