The location of conduction abnormality including activation slowing and wavefront discontinuity, which often corresponds to the critical zones reentrant circuit in scar-mediated ventricular tachycardia (VT), is affected by direction during substrate mapping. We hypothesized that an abrupt change paced-QRS morphologies may occur at region with abnormality. This study assessed velocity mapping le...

The majority of the studies on V˙O2 kinetics in pediatric populations investigated gender differences in prepubertal children during submaximal intensity exercise, but studies are lacking in adolescents. The purpose of this study was to test the hypothesis that gender differences exist in the V˙O2 and heart rate (HR) kinetic responses to moderate (M) and heavy (H) intensity exercise in adolesce...

A simplified method has been developed for the determination of antibody-hapten association kinetics that permits the study of high affinity interactions with second order forward rate constants of the order of 10-7 to 10-8 M-1 sec-1. Use of tritiated haptens of high specific activity and antibodies of high affinity allows reactions to be run at initial hapten and antibody concentrations of the...

A cooperative program of seismic refraction profiling was completed in the vicinity of the Puerto Rico Trench by Hudson Laboratories, Woods Hole, Lamont, and Texas A. & M. Profiles completed near the western end of the Trench were analyzed at Hudson Laboratories. Five seismic layers are indicated below the water layer. The thickness/velocity relationships are as follows: 5.1 km of 1.5 km/sec. (...

The aim of the present study was to determine whether 1 week of training cessation can affect exercise performance in well-trained soccer players. Upon the completion of a competitive season, 11 male soccer players went through 1-week training cessation. Performances in the 5-m (1.05±0.04 sec vs 1.02±0.03 sec, P=0.03) and 10-m (1.79±0.06 sec vs 1.74±0.06 sec, P=0.03) sprints were significantly ...

The reversible potassium channel blocker 4-aminopyridine is effective in the treatment of numerous cerebellar dysfunctions, such as episodic ataxia type 2 and downbeat nystagmus syndrome. In 2011, its sustained release form, dalfampridine, was admitted in Europe for the treatment of walking difficulties in patients with multiple sclerosis (MS). Here we report the case of a 44-year old patient w...

Aim of this study was to evaluate in patients with progressive external ophthalmoplegia (PEO) the left ventricular function by standard echocardiography and tissue Doppler imaging (TDI) analysis. Twenty patients with PEO (55.4 ± 17.5 years) and 20 ageand sex-matched healthy subjects underwent standard echocardiography with TDI analysis to assess left ventricular function. TDI was performed by p...