Introduction: Age-related macular degeneration (AMD) is one of the major causes of visual loss among the elderly. It causes degeneration of cells in the macula. Early diagnosis can be helpful in preventing blindness. Drusen are the initial symptoms of AMD. Since drusen have a wide variety, locating them in screening images is difficult and time-consuming. An automated digital fundus photography...

 Background: Age-related macular degeneration (AMD) is the leading cause of visual impairment and blindness in elderly population in the developing countries. Previous epidemiological studies revealed various potential modifiable risk factors for this disease. The purpose of this study was to evaluate the prevalence of AMD among elderly living in Babol, North of Iran.  Methods:  The study ...

background: half of the cases of vision loss in people under 60 years of age have been attributed to age-related macular degeneration (amd). this is a multifactorial disease with late onset. it has been demonstrated that many different genetic loci are implicated in the risk of developing amd in different populations. in the current study, we investigated the association of high-temperature ‎re...

background: alpha methyldopa (amd) is a well-known treatment for the pregnancy induced hypertension and commonly used in several countries. indeed the possible effect of amd on the behavioral activities of offspring, whom are exposed during fetus period, has not been studied. the present study evaluated the possible effect of maternal administration of amd on the rat offspring memory in the gro...

background: age-related macular degeneration (amd) is one of the leading causes of visual loss among people aged 65 yr and older. the pathophysiology of amd is poorly understood. the purpose of this study was to evaluate the relationship between serum lipid concentrations and age-related macular degeneration. methods: in this case-control study, total cholesterol (tch), low density lipoprotein ...

Background & Aims: To investigate the association of CFI p.Gly119Arg polymorphism with Age-related macular degeneration (AMD). Materials & Methods: In this case-control study, the association of p.Gly119Arg polymorphism in CFI gene was investigated in 65 patients suffering from AMD and150 healthy age, sex and ethnicity matched unrelated people as control group. Both of the case and cont...

Background: We aimed here to investigate the association between alleles and genotypes of APOE and Age-related macular degeneration (AMD) development. Materials and Methods: After ophthalmological examination, 120 patients with confirmed AMD and 120 healthy controls were enrolled in the study. The polymorphic segment of APOE gene was PCR-amplified and sequenced to determine the frequency distr...