Nowadays energy saving is one of the crucial aspects in decisions. One of the approaches in this case is efficient use of resources in the industrial systems. Studies in real manufacturing systems indicating that one or more machines may also act as the Bottleneck Resource/ Resources (BR). On the other hand according to the Theory of Constraints (TOC), the efficient use of resources in manufact...

coq10 and lycopene are isoprenoid compounds with nutraceutical and pharmaceutical benefits. in this study, the effect of concomitant lycopene biosynthesis on coq10 accumulation in transformed escherichia coli dh5α was studied. a lycopene production pathway including geranylgeranyl diphosphate synthase (crte), phytoene synthase (crtb), and phytoene desaturase (crti) from erwinia herbicola was co...

This paper deals with the service performance analysis and improvement using discrete event simulation has been used. The simulation of the health care has been done by arena master development 14-version software. The performance measurement for this study are patients output, service rate, service efficiency and it is directly related to waiting time of patients in each service station, work ...

Heterologous overexpression of functional membrane proteins is a major bottleneck of structural biology. Bacteriorhodopsin from Halobium salinarum (bR) is a striking example of the difficulties in membrane protein overexpression. We suggest a general approach with a finite number of steps which allows one to localize the underlying problem of poor expression of a membrane protein using bR as an...

In this paper, we model a research-and-development project as consisting of several modules, with each module containing one or more activities. We examine how to schedule the activities of such a project in order to maximize the expected profit when the activities have a probability of failure and when an activity’s failure can cause its module and thereby the overall project to fail. A module...

We propose a framework that enables the acquisition of annotation-heavy resources such as syntactic dependency tree corpora for low-resource languages by importing linguistic annotations from high-quality English resources. We present a large-scale experiment showing that Chinese dependency trees can be induced by using an English parser, a word alignment package, and a large corpus of sentence...

We introduce (super) polynomial bottleneck games, where the utility costs of the players are (super) polynomial functions of the congestion of the resources that they use, and the social cost is determined by the worst congestion of any resource. In particular, the delay function for any resource r is of the form CMr r , where Cr is the congestion measured as the number of players that use r, a...

1Over the past few years, several approaches to scheduling have been proposed that attempt to reduce tardiness and inventory costs by opportunistically (i.e. dynamically) combining resource-centered perspective to schedule bottleneck resources, and a job-centered perspective to schedule non-bottleneck operations on a job by job basis. Rather than relying on their initial bottleneck analysis, th...