background: we have previously reported multiple health benefits in individuals following the christian-based fasting protocol known as the daniel fast (df). however, our prior work has involved only short-term (21-day) assessments. for dietary modification to have a profound impact on health, compliance to the dietary plan must be established for the long-term. materials and methods we determi...

background: it has been shown that dietary restriction in the form of every other day fasting (eodf) has neuroprotective effects. the mechanisms of these effects are unknown yet. recently, it has claimed that dietary restriction can reset circadian and regulate irregular rhythms. previous studies have demonstrated that dietary restriction can change melatonin production and secretion. since mel...

Background: We have previously reported multiple health benefits in individuals following the Christian-based fasting protocol known as the Daniel Fast (DF). However, our prior work has involved only short-term (21-day) assessments. For dietary modification to have a profound impact on health, compliance to the dietary plan must be established for the long-term. Materials and Methods We determi...

Background and Objectives: Apoptosis plays a key role in pathogenesis of various cardiovascular diseases due to loss of terminally differentiated cardiac myocytes. Therefore, the aim of this study was to investigate effects of combined dietary restriction and aerobic training on indices of myocardial apoptosis in male rats. Materials and Methods: In this study, 32 three-month-old male rats wer...

Dietary restriction delays the incidence and decreases the growth of various types of tumours, but the mechanisms underlying the sensitivity of tumours to food restriction remain unknown. Here we show that certain human cancer cell lines, when grown as tumour xenografts in mice, are highly sensitive to the anti-growth effects of dietary restriction, whereas others are resistant. Cancer cells th...

Dietary restriction is beneficial in preventing a multitude of diseases, many of which may involve the immune system in their etiology. Recent reports examining dietary restriction focused on T lymphocytes and macrophages. Dietary restriction delays the onset of T-lymphocyte–dependent autoimmune disease; this may be attributed to improved antioxidant defense mechanisms, blunting shifts in T-lym...