نتایج جستجو برای: Formalin-induced pain Histamine

تعداد نتایج: 1229136  

Journal: :veterinary research forum 2010
esmaeal tamaddonfard

in the present study, the effects of intracerebroventricular (icv) administration of normal saline (control), histamine, mepyramine (a histamine h1-receptor antagonist) and ranitidine (a histamine h2-receptor antagonist) were investigated on the formalin-induced pain in rabbits. subcutaneous (sc) injection of a formalin (100 μl, 5%) solution into the ventral surface of the right hind paw was pe...

Journal: :iranian journal of basic medical sciences 0
esmaeal tamaddonfard department of basic sciences, faculty of veterinary medicine, urmia university, urmia, iran nasrin hamzeh gooshchi faculty of veterinary medicine, urmia university, urmia, iran

objective(s): the present study investigated the effects of microinjection of histamine and histamine h1, h2, and h3 receptor antagonists, chlorpheniramine, ranitidine and thioperamide, respectively into the primary somatosensory cortex (psc) on inflammatory pain.   material and methods: two stainless steel guide canulas were bilaterally implanted into the psc of anaesthetized rats. inflammator...

Esmaeal Tamaddonfard, Nasrin Hamzeh Gooshchi

  Objective(s): The present study investigated the effects of microinjection of histamine and histamine H1, H2, and H3 receptor antagonists, chlorpheniramine, ranitidine and thioperamide, respectively into the primary somatosensory cortex (PSC) on inflammatory pain.   Material and Methods: Two stainless steel guide canulas were bilaterally implanted into the PSC of anaesthetized rats. Inf...

In the present study, the effects of intracerebroventricular (ICV) administration of normal saline (control), histamine, mepyramine (a histamine H1-receptor antagonist) and ranitidine (a histamine H2-receptor antagonist) were investigated on the formalin-induced pain in rabbits. Subcutaneous (SC) injection of a formalin (100 μl, 5%) solution into the ventral surface of the right hind paw was pe...

Journal: :تحقیقات دامپزشکی 0
اسماعیل تمدن فرد گروه علوم پایه، دانشکده دامپزشکی، دانشگاه ارومیه ارفین عظیم پوران دانش آموخته دانشکده دامپزشکی، دانشگاه آزاد اسلامی تبریز بابک بهجت دانش آموخته دانشکده دامپزشکی، دانشگاه آزاد اسلامی تبریز

objective: to investigate the effect of intracerebroventricular injection of histamine on pain induced by subcutaneous iniection of formalin in the left ear of rabbit and the effect of the amine on morphine analgesia and naloxone hyperalgesia. design: experimental study. animals: sixty - six male new zealand white rabbits weighing 2.640.16kg. procedure: intracerebroventricular injections of the...

حجازیان, الهام السادات, حجازیان, سید حسن, صادقیان, محمد رضا,

Background and Objectives: Aerobic exercise or cardio is defined as a physical exercise that causes high oxygen consumption compared to the rest and conducted to increased cardiorespiratory intensity. Different substances, can inhibit pain occurred through opioids, histaminergic, and cholinergic receptors. This study was done to determine the role of aerobic exercise in pain by histamine rece...

Journal: :Indian journal of physiology and pharmacology 2008
Ali Mojtahedin Esmaeal Tamaddonfard Ali Zanboori

In the present study, effects of intracerebroventricular (icv) administration of histamine, mepyramine (H1-receptor antagonist) and famotidine (H2-receptor antagonist) have been investigated on the formalin test in rats. Subcutaneous injection of formalin (50 microl, 1%) into the ventral surface of the left hind paw produced a marked biphasic pain response (first phase: 0-5 min and second phase...

تمدن فرد, اسماعیل, خلیل زاده, عماد, سیدنژاد, صونا, عرفان پرست, امیر, فرشید , امیر عباس,

  Background & Aims : Brain histamine, through H3 receptor, has an important role in central perception of pain. The present study investigated the effects of intra-hippocampal microinjection of histamine and thioperamide (a histamine H3 antagonist) on tonic pain in orofacial region of rats.   Materials & Methods: In 72 male Wistar rats two guide cannulae were implanted into the dorsal hippocam...

2014
Esmaeal Tamaddonfard Nasrin Hamzeh-Gooshchi

OBJECTIVE(S) The present study investigated the effects of microinjection of histamine and histamine H1, H2, and H3 receptor antagonists, chlorpheniramine, ranitidine and thioperamide, respectively into the primary somatosensory cortex (PSC) on inflammatory pain. MATERIAL AND METHODS Two stainless steel guide canulas were bilaterally implanted into the PSC of anaesthetized rats. Inflammatory ...

Journal: :Pharmacological reports : PR 2011
Esmaeal Tamaddonfard Amir Erfanparast Amir Abbas Farshid Emad Khalilzadeh

The present study explored the interaction between histaminergic and opioidergic systems at the level of the hippocampus in modulation of orofacial pain by intra-hippocampal microinjections of histamine, pyrilamine (an antagonist of histamine H(1) receptors), ranitidine (an antagonist of histamine H(2) receptors), morphine (an opioid receptor agonist) and naloxone (an opioid receptor antagonist...

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