نتایج جستجو برای: Insulin receptor

تعداد نتایج: 746257  

Objective(s): Diabetes mellitus has been suggested to be the most common metabolic disorder associated with magnesium deficiency. This study aimed to investigate the effects and mechanisms of magnesium supplementation on insulin receptor activity in elderly type 2 diabetes using a rat model and to provide experimental evidence for insulin resistance improvement by magn...

Journal: :international journal of reproductive biomedicine 0
fahimeh ramezani tehrani maryam daneshpour somayeh hashemi maryam zarkesh feridoun azizi

background: polycystic ovary syndrome (pcos) is a complex disease having both genetic and environmental components and candidate genes on obesity and insulin metabolism have been hypothesized to be involved in its etiology. objective: we examined the possible association of adiponectin and insulin receptor gene polymorphisms with pcos. materials and methods: a total of 186 women with pcos using...

Journal: :مجله غدد درون ریز و متابولیسم ایران 0
آزیتا پروانه تفرشی a. parvaneh tafreshi پژوهشگاه ملی مهندسی ژنتیک و زیست فناوری تهران، صندوق پستی 161-14965، دکتر آزیتا پروانه تفرشی راضیه جلال r jalal شمیلا درویش علی پور s darvishalipour حوری سپهری h sepehri خسرو عادلی k adeli

abstract introduction: there is limited knowledge available on the metabolism of glucose in the brain, an insulin insensitive organ. insulin receptors hybridize with insulin like growth factor receptor (igf-i) to transduce the signals in different areas of the brain. in this article we aimed at investigating whether the expression of igf-i receptor and igf-i binding proteins (igfbp1) is changed...

Journal: :journal of research in medical sciences 0
marzieh kafeshani mohsen janghorbani rasol salehi mohammad kazemi mohammad hasan entezari

background: insulin receptor substrate (irs) type 1 is a main substrate for the insulin receptor, controls insulin signaling in skeletal muscle, adipose tissue, and the vascular, so it is an important candidate gene for insulin resistance (ir). we aimed to compare the  effects of the dietary approaches to stop hypertension (dash) and usual dietary advices (uda) on irs1 gene expression in women ...

جلال, راضیه, درویش علی پور, شمیلا, سپهری, حوری, عادلی, خسرو, پروانه تفرشی, آزیتا,

Abstract Introduction: There is limited knowledge available on the metabolism of glucose in the brain, an insulin insensitive organ. Insulin receptors hybridize with insulin like growth factor receptor (IGF-I) to transduce the signals in different areas of the brain. In this article we aimed at investigating whether the expression of IGF-I receptor and IGF-I binding proteins (IGFBP1) is change...

Journal: :مجله دانشگاه علوم پزشکی شهرکرد 0
اکرم منصوری بیدکانی akram mansouri-bidekani biology dept, faculty of basic sciences, shahrekord university, shahrekord, i.r. iran, tel:شهرکرد، دانشگاه شهرکرد، دانشکده علوم پایه، گروه زیست شناسی، تلفن: 09387388036، فریبا اسماعیلی fariba esmaeili biology dept., shahrekord university, shahrekord, i.r. iranگروه زیست شناسی، دانشگاه شهرکرد، شهرکرد، ایران فریبا هوشمند fariba houshmand medical plants research center, shahrekord university of medical sciences, shahrekord, i.r. iran.مرکز تحقیقات گیاهان داروئی، دانشگاه علوم پزشکی شهرکرد، شهرکرد، ایران. زهره حاجی شریفی zohre hajisharifi biology dept., shahrekord university, shahrekord, i.r. iranگروه زیست شناسی، دانشگاه شهرکرد، شهرکرد، ایران

background and aims: understanding β-cell function at the molecular level will likely facilitate the development of β-cells manufacture techniques. the aim of the present study was to investigate the pancreatic and duodenal homeobox 1 (pdx-1) gene expression into dtz-stained cellular clusters originating from emberyonal carcinoma cells. methods: this implemental -fundamental study was accomplis...

Objective(s): Type 1 diabetes (T1D) is an autoimmune disease resulting from inflammatory destruction of islets β-cells. Nowadays, progress in cell therapy, especially mesenchymal stem cells (MSCs) proposes numerous potential remedies for T1D. We aimed to investigate the combination therapeutic effect of these cells with insulin and metformin on neuropeptide Y, melanoco...

Journal: :the journal of tehran university heart center 0
reza meshkani department of biochemistry, faculty of medicine, tehran university of medical sciences, tehran, iran khosrow adeli clinical biochemistry, the hospital for sick children, university of toronto, toronto, ontario, cana

the worldwide prevalence of insulin resistant states such as the metabolic syndrome has grown rapidly over the past few decades. the metabolic syndrome is a constellation of common metabolic disorders that promote the development of atherosclerosis and cardiovascular disease. studies in both human and animal models suggest that hepatic inflammation and insulin resistance are key initiating fact...

ارکانی, مارال , زالی, محمد رضا, صفائی, اکرم, فاطمی, سید رضا, محبی, سید رضا, واحدی, محسن , وفائی, محمد , کریمی, خاتون ,

Background and purpose: Insulin regulates cell growth and apoptosis by binding to its receptor (INSR). Many studies show that variation in insulin pathway play a plausible role in the development of colorectal cancer (CRC). The goal of this study was to evaluate the incidence of insulin receptor (INSR rs1799817) in people attending Taleghani Hospital and to investigate the role of this poly...

Journal: :مجله دانشگاه علوم پزشکی کرمانشاه 0
golbarg ghiasi 1. student research committee, kermanshah university of medical sciences, kermanshah. 2. pharmacoeconomy and pharmaceutical management, faculty of pharmacy, tehran university of medical sciences, tehran amir farshchi 1. student research committee, kermanshah university of medical sciences, kermanshah. 2. pharmacoeconomy and pharmaceutical management, faculty of pharmacy, tehran university of medical sciences, tehran ali pourmotabbed dept. of phisiology, school of medicine, kermanshah university of medical sciences, kermanshah gholam-reza bahrami dept. of pharmacology, school of pharmacy, kermanshah university of medical sciences, kermanshah sayyed-ershad nedaee dept. of phisiology, school of medicine, kermanshah university of medical sciences, kermanshah

background: diabetes mellitus is one of the most important diseases in all over the world. insulin and its receptor are found in specific area of cns with a variety of regions-specific functions different from its role in direct glucose regulation in the periphery. the hippocampus and cerebral cortex distributed insulin and insulin receptor has been shown to be involved in brain cognitive funct...

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