Background: Heart failure (HF) has become one of the most prevalent cardiovascular problems worldwide. Considering the beneficial effects of probiotics on human health, we aimed to investigate the anti-inflammatory effect of oral administration of Lactobacillus paracasei in HF induced by isoproterenol. Methods: Forty Wistar male rats weighing 80g on average were randomly assigned to five grou...

myocardial infarction (mi) is a common presentation of the ischemic heart disease. lavandula angustifolia is a herbaceous plant with antioxidative effects.this study was designed to investigate the cardioprotective effects of lavandula angustifolia essential oil against isoproterenol-induced mi in rats.the dried sample was subjected to hydrodistillation by using a clevenger and the oils were dr...

In the present study, we investigated the effects of histidine and vitamin C (alone or in combination) treatments against isoproterenol (a β-adrenergic receptor agonist)-induced acute myocardial infarction in rats. We used propranolol (a β-adrenergic receptor blocker) to compare the results. Rats were given intraperitoneal injections of histidine (40 mg kg-1) and vitamin C (40 mg kg<...

Background: Heart Failure (HF) has become one of the most prevalent cardiovascular problems worldwide. Considering beneficial effects probiotics on human health, we aimed to investigate anti-inflammatory effect oral administration Lactobacillus paracasei in HF induced by isoproterenol. Methods: Forty Wistar male rats weighing 80g average were randomly assigned five groups eight each: control, p...

BACKGROUND Long-term β-adrenergic receptor (β-AR) blockade reduces mortality in patients with heart failure. Chronic sympathetic hyperactivity in heart failure causes sustained β-AR activation, and this can deplete Ca(2+) in endoplasmic reticulum (ER) leading to ER stress and subsequent apoptosis. We tested the effect of β-AR blockers on ER stress pathway in experimental model of heart failure....