background: activated normal platelets undergo many biochemical and morphological changes, some of which are apoptotic. platelet derived microparticles and shrinked platelets as hallmark of platelet activation and apoptosis disperse surfaces containing procoagulant activity around injured vessels and tissues. this study was conducted to determine microparticles formation and platelet shrinkage ...

Background: Activated normal platelets undergo many biochemical and morphological changes, some of which are apoptotic. Platelet derived microparticles and shrinked platelets as hallmark of platelet activation and apoptosis disperse surfaces containing procoagulant activity around injured vessels and tissues. This study was conducted to determine microparticles formation and platelet shrinkage ...

objectives: platelets are anucleated fragments derived from megakaryocytes. it has been demonstrated that platelets play a role in hemostasis and innate immunity. in addition, platelets have a cd40 ligand which is an important molecular marker in motivating immune cells. thus, platelets also have a role in adaptive immunity as seen by their ability to activate b cells. since human platelet micr...

Idiopathic thrombocytopenia purpura (ITP) is an autoimmune disorder characterized by isolated thrombocytopenia and mucocutaneous bleeding. The former has a primary role in the diagnosis and treatment of ITP. One of the leading causes of miscounted platelets in patients who suffer from ITP is giant platelets which may indicate factitiously a severe false thrombocytopenia. Here, a case of macroth...

introduction: in this study the evaluation of a platelet-based maximum penalized likelihood estimation (mple) for denoising spect images was performed and compared with other denoising methods such as wavelets or butterworth filtration. platelet-based mple factorization as a multiscale decomposition approach has been already proposed for better edges and surfaces representation due to poisson n...

conclusions helicobacter pylori infection has a significant effect on platelet count in patients with citp and h. pylori eradication therapy should be considered as an important factor in platelet count recovery in citp patients. results from a total of 23 patients with citp, 43% (10) of the cases were h. pylori positive and after eradication therapy, eight patients (80%) were successfully trea...

background nonalcoholic fatty liver disease has become a worldwide challenge. liver biopsy remains the single most reliable approach to determine the severity of this disease. as patients with nonalcoholic fatty liver disease require close follow-up, performing this invasive method repeatedly seems impractical; therefore, designing a noninvasive system to follow up patients has become a common ...