objectives: we have investigated the effect of a saffron supplement, given at a dose of 100 mg/kg, on prooxidant-antioxidant balance (pab) in individuals with metabolic syndrome. materials and methods: a randomized, placebo-controlled trial design was used in 75 subjects with metabolic syndrome who were randomly allocated to one of two study groups: (1) the case group received 100mg/kg saffron ...

aim: we conducted this study to investigate the role of ramadan fasting on oxidative stress. materials and method: 23 people (16 male, 7 female) aged between 25 and 65 years were recruited in this study. 10cc venous blood samples were taken after 8- to 10- hours fasting on 2 different times: a week before ramadan and at the end of ramadan (day 27). portions of the serum samples were used immedi...

background & aim: the most common primary brain tumors of the central nervous system are gliomas. among a number of different biomolecular events, a strong relation between oxidative stress pathways and the development of this cancer has been proved. oxidative stress (os) is the consequence of an imbalance between pro-oxidants and antioxidants towards pro-oxidants. the pro-oxidants cause lipid ...

objective(s) comparison of prooxidant-antioxidant balance (pab) assay with crocin assay. materials and methods twenty eight serum samples were chosen, pab and the total antioxidant capacity were measured by pab assay and crocin, respectively, and the correlation of both assays, along with their correlation with other clinical and biochemical parameters, were determined. results a significant ne...

The chronic disorder of arterial circulation in the lower extremities due to the atherosclerotic injuries of the femoral-popliteal-tibial arteries was accompanied by the shift of the blood prooxidant-antioxidant balance towards more active free radical oxidation and by a depletion of antioxidant system. After restoring arterial blood flow in the ischemic lower extremities this balance was shift...

Under normal conditions, antioxidants at the corneal surface are balanced with the production of reactive oxygen species without any toxic effects. Danger from oxidative stress appears when natural antioxidants are overwhelmed leading to antioxidant/prooxidant imbalance. The aim of the present study was to examine the activities of enzymes contributing to the antioxidant/prooxidant balance in n...

Objective(s) Comparison of prooxidant-antioxidant balance (PAB) assay with crocin assay. Materials and Methods Twenty eight serum samples were chosen, PAB and the total antioxidant capacity were measured by PAB assay and crocin, respectively, and the correlation of both assays, along with their correlation with other clinical and biochemical parameters, were determined. Results A significa...

Flavonoids have demonstrated in vivo and in vitro leishmanicidal, trypanocidal, antioxidant, and prooxidant properties. The chemotherapy of trypanosomiasis and leishmaniasis lacks efficacy, presents high toxicity, and is related to the development of drug resistance. Thus, a series of 40 flavonoids were investigated with the purpose of correlating these properties via structure and activity ana...

Aim: we conducted this study to investigate the role of Ramadan fasting on oxidative stress. Materials and method: 23 people (16 male, 7 female) aged between 25 and 65 years were recruited in this study. 10cc Venous blood samples were taken after 8- to 10- hours fasting on 2 different times: a week before Ramadan and at the end of Ramadan (day 27). Portions of the serum samples were used immedi...

Antioxidant-prooxidant imbalance is one of the key mechanisms acute blood loss and ischemic-reperfusion syndrome. Under these conditions, level ceruloplasmin (CP) plays an important role, enhancing antioxidant protection promoting hematopoiesis, exhibiting ferrooxidase action. However, in this case, state antioxidant-prooxidant balance spleen content CP serum studied insufficiently, thus there ...