نتایج جستجو برای: antibacterial peptide

تعداد نتایج: 198023  

Journal: :international journal of molecular and cellular medicine 0
hassan hoda biological control department, national institite of plant protection, amol, iran. fatemeh elmi department of chemistry, university of mazandaran, babolsar, iran.سازمان اصلی تایید شده: دانشگاه مازندران (mazandaran university) maryam mytra elmi cellular and molecular biology research center, and paramedical department, babol university of medical sciences, babol, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (babol university of medical sciences)

abstract background antibiotic resistance makes antimicrobial peptides (amps) agents an alternative for treatment of pathogenic diseases. they are isolated from various animals invertebrates, vertebrates and plants. the present study shows the electrophoretic pattern of protein and peptides from vicia faba seed and reports our first attempt to study the antibacterial activity of vicia faba seed...

Abstract Background and purpose: Multiple drug-resistant (MDR) bacterial strains have spread in different parts of hospitals. The aim of this study was to design and synthesize an effective hybrid peptide by combining different parts of two peptides to achieve the highest antibacterial activity and its inhibitory effect against Staphylococcus aureus and Pseudomonas aeruginosa strains. Materia...

Journal: :The Journal of biological chemistry 1995
S Hara M Yamakawa

A novel antibacterial peptide that shows antibacterial activity against Staphylococcus aureus was isolated from the hemolymph of the silkworm, Bombyx mori. The novel peptide consisted of 42 amino acids and was highly basic. This peptide indicated no significant similarity with other antibacterial peptides. The peptide showed antibacterial activity against several Gram-negative and -positive bac...

Journal: :jundishapur journal of microbiology 0
hamid babavalian applied biotechnology research center, baqiyatallah university of medical sciences, tehran, ir iran ali mohammad latifi applied biotechnology research center, baqiyatallah university of medical sciences, tehran, ir iran; applied biotechnology research center, baqiyatallah university of medical sciences, tehran, ir iran. tel/fax: +98-2188617712, e-mail:; mohammad ali shokrgozar, national cell bank of iran, pasteur institute of iran, tehran, ir iran. tel: 98-2166492595 mohammad ali shokrgozar national cell bank of iran, pasteur institute of iran, tehran, ir iran; applied biotechnology research center, baqiyatallah university of medical sciences, tehran, ir iran. tel/fax: +98-2188617712, e-mail:; mohammad ali shokrgozar, national cell bank of iran, pasteur institute of iran, tehran, ir iran. tel: 98-2166492595 shahin bonakdar national cell bank of iran, pasteur institute of iran, tehran, ir iran sajjad mohammadi national cell bank of iran, pasteur institute of iran, tehran, ir iran mehrdad moosazadeh moghaddam applied biotechnology research center, baqiyatallah university of medical sciences, tehran, ir iran

conclusions this study showed that compared to standard drug treatment, treatment with hydrogel containing peptide had substantial antibacterial effects on s. aureus wound infections in mice. results the highest and lowest numbers of wounds were observed on day 2 in the negative and positive control groups, respectively. during the 8-day period, the positive control and hydrogel containing pept...

Background and Objective: Antimicrobial peptides have attracted significant attention in recent decades because of their properties, such as rapid bactericidal effects, having a wide spectrum of activity, and a rare development of drug resistance. The purpose of this study was to examine the antibacterial activity of a peptide derived from the lactoferrin isolated from camel milk against Staphy...

2011
Jeong Min Kim Sujung Jang Mi-Hwa Yang Hyeongjin Cho Keun-Hyeung Lee

We synthesized peptide-resin conjugates (1 and 2) by immobilizing β-sheet antibacterial peptide and α helical antibacterial peptide on PEG-PS resin, respectively. Conjugate 1 showed considerable antibacterial activity in various conditions, whereas conjugate 2 did not exhibit antibacterial activity. The growths of various bacteria were inhibited by conjugate 1 even at lower concentrations than ...

2011
J. H. Wang C. C. Wu J. Feng

The objective of this study was to evaluate the effect of dietary supplementation of antibacterial peptide and zinc methionine on performance and some serum biochemical parameters of weaned piglets. Rongchang male piglets (28 days of age, initial weight 8.4 ± 0.65 kg) were used. All piglets were randomly allotted to four diets including the control group, the antibacterial peptide (AP) group co...

2017
Hao Yang Jingyu Fu Youyun Zhao Huiping Shi Hua Hu Hongliang Wang

BACKGROUND The aim of this study was to investigate the antimicrobial property of peptide LL-37 sequences. MATERIAL AND METHODS Humanized antibacterial peptide LL-37 and the mutant were prepared by chemical synthesis. The physicochemical properties of antibacterial peptide LL-37 were analyzed by SWISS-MODEL online prediction tool. Molecular docking between antibacterial peptide LL-37 fragments ...

Journal: :The Journal of clinical investigation 1992
R P Darveau J Blake C L Seachord W L Cosand M D Cunningham L Cassiano-Clough G Maloney

A peptide (C13) corresponding to the last 13 amino acids of the carboxyl terminus of human platelet factor IV was found to be antibacterial. Amino acid substitutions predicted to disrupt either the amphipathic or alpha-helical nature of C13 rendered the peptide inactive. Antibacterial activity was demonstrated in normal human serum on bacteria which had been previously exposed to low levels of ...

2016
Jibin Sha Chenggang Zhang

BACKGROUND hGlyrichin is a novel human antimicrobial peptide rich in glycine. The previous study of known human antimicrobial peptides indicated that in an eligible range, the greater corresponding antibacterial activity was consisted with the shorter peptide sequence. FINDINGS Two peptides named pCM19 and pCM12 were synthesized and the antibacterial activity assay results showed that these p...

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