نتایج جستجو برای: autoclaved leishmania major alm

تعداد نتایج: 630960  

Journal: :iranian journal of pharmaceutical research 0
mahmoodreza jaafari biotechnology and nanotechnology research center, school of pharmacy, mashhad university of medical sciences (mums), mashhad, iran mohsen tafaghodia nanotechnology research center, school of pharmacy, mashhad university of medical sciences, p.o. box 91775-1365, mashhad, iran maryam maryam eskandari nanotechnology research center, school of pharmacy, mashhad university of medical sciences, p.o. box 91775-1365, mashhad, iran ali khamesipour center for research and training in skin diseases and leprosy, tehran university of medical sciences, tehran, iran

leishmania antigens are weak immunogens and need to be potentiated by various adjuvants and delivery systems. alginate microspheres as an antigen delivery system and quillaja saponins (qs) as an immunoadjuvant have been used to enhance the immune response against autoclaved leishmania major (alm). microspheres were prepared by an emulsification technique and characterized for size, encapsulatio...

Leishmania antigens are weak immunogens and need to be potentiated by various adjuvants and delivery systems. Alginate microspheres as an antigen delivery system and Quillaja saponins (QS) as an immunoadjuvant have been used to enhance the immune response against Autoclaved Leishmania major (ALM). Microspheres were prepared by an emulsification technique and characterized for size, encapsulatio...

Leishmania antigens are weak immunogens and need to be potentiated by various adjuvants and delivery systems. Alginate microspheres as an antigen delivery system and Quillaja saponins (QS) as an immunoadjuvant have been used to enhance the immune response against Autoclaved Leishmania major (ALM). Microspheres were prepared by an emulsification technique and characterized for size, encapsulatio...

Journal: :iranian journal of public health 0
m.mohebali e. fallah sh. jamshidi h. hajjaran

in this study, 16 eligible dogs were randomly divided in to 4 groups. group 1, 2, 3 and 4 received autoclaved leishmania infantum with bcg (ali+bcg), autoclaved leishmania major + bcg (alm + bcg), bcg alone and normal saline, respectively. dogs received the vaccines intradermally 3 times at 30 days intervals. all dogs were followed up 2 months intervals by leishmanin skin test and anti -leishma...

2016
Mohsen Tafaghodi Maryam Eskandari Ali Khamesipour Mahmoud Reza Jaafari

Leishmania antigens are weak immunogens and need to be potentiated by various adjuvants and delivery systems. Alginate microspheres as antigen delivery system and Quillaja saponins (QS) as immunoadjuvant have been used to enhance the immune response against Autoclaved Leishmania major (ALM). Microspheres were prepared by an emulsification technique and characterized for size, encapsulation effi...

Journal: :Journal of microencapsulation 2012
Abbas Pardakhty Mojtaba Shakibaie Hamid Daneshvar Ali Khamesipour Tayebe Mohammadi-Khorsand Hamid Forootanfar

In this study, different positively charged niosomal formulations containing sorbitan esters, cholesterol and cetyl trimethyl ammonium bromide were prepared by film hydration method for the entrapment of autoclaved Leishmania major (ALM). Size distribution pattern and stability of niosomes were investigated by laser light scattering method and ALM encapsulation per cent was measured by the bici...

Journal: :iranian journal of basic medical sciences 0
mohsen tafaghodi school of pharmacy, mashhad university of medical sciences, mashhad, iran pharmaceutical research center, mashhad university of medical sciences, mashhad, iran abolghasem sajadi tabassi school of pharmacy, mashhad university of medical sciences, mashhad, iran pharmacological research center of medicinal plants, mashhad university of medical sciences, mashhad, iran nafiseh amiri school of pharmacy, mashhad university of medical sciences, mashhad, iran

objective(s) several antigens, adjuvants and delivery systems have been evaluated for induction of protective immune responses against leishmaniasis, but most of them have been inefficient. in this study, plga nanospheres as antigen delivery system cpg-odn as an immunoadjuvant for increasing the immune responses against autoclaved leishmania major (alm) were prepared and characterized. material...

Abolghasem Sajadi Tabassi Mohsen Tafaghodi, Nafiseh Amiri

Objective(s) Several antigens, adjuvants and delivery systems have been evaluated for induction of protective immune responses against Leishmaniasis, but most of them have been inefficient. In this study, PLGA nanospheres as antigen delivery system CpG-ODN as an immunoadjuvant for increasing the immune responses against Autoclaved Leishmania major (ALM) were prepared and characterized. Materi...

Maryam Payan Mohsen Tafaghodi, Syyed Abolghasem Sajadi Tabasi

     The goal of this study was to prepare and characterize alginate microspheres as an antigen delivery system and adjuvant for immunization against leishmaniasis. Microspheres encapsulated with autoclaved Leishmania major (ALM) and Quillaja saponin (QS) were prepared by an emulsification technique and characterized for size, encapsulation efficiency and release profile of encapsulate...

Journal: :The Journal of Experimental Medicine 2002
Elizabeth G. Rhee Susana Mendez Javeed A. Shah Chang-you Wu Joanna R. Kirman Tara N. Turon Dylan F. Davey Heather Davis Dennis M. Klinman Rhea N. Coler David L. Sacks Robert A. Seder

CpG oligodeoxynucleotides (ODN) have potent effects on innate and adaptive cellular immune responses. In this report, the ability of CpG ODN to confer long-term immunity and protection when used as a vaccine adjuvant with a clinical grade of leishmanial antigen, autoclaved Leishmania major (ALM), or a recombinant leishmanial protein was studied. In two different mouse models of L. major infecti...

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