Objective(s): Pseudomonas aeruginosais a Gram-negative and aerobic rod bacterium that displays mucoid and non-mucoid phenotype. Mucoid strains secrete alginate, which is the main agent of biofilms in chronic P. aeruginosa infections, show high resistance to antibiotics; consequently, the biological disruption of mucoid P. aeruginosa biofilms is an attractive area of study for researchers. Algin...

Biofilms and microbial aggregates are the common mechanisms for the survival of bacteria in nature. In other words, the ability to form biofilms has been regarded as a virulence factor. Microbial biofilms play an essential role in several infectious diseases such as pulp and periradicular pathosis. The aim of this article was to review the adaptation mechanisms of biofilms, their roles in pulpa...

background and objectives: there is increasing emergence of multidrug resistant pseudomonas aeruginosa (mdrpa) strains and drug resistance is positively-correlated with biofilm-forming ability. since about 10% of p. aeruginosa genome is controlled by quorum sensing (qs), alteration in its antibiotic susceptibility by targeting qs was the focus of the present study. materials and methods : one d...

A filter disk assay was used to investigate the penetration of antifungal agents through biofilms containing single and mixed-species biofilms containing Candida. Fluconazole permeated all single-species Candida biofilms more rapidly than flucytosine. The rates of diffusion of either drug through biofilms of three strains of Candida albicans were similar. However, the rates of drug diffusion th...

normal 0 false false false en-us x-none fa background : the growing interest in filler injection requires a more comprehensive knowledge about the complications of this procedure. methods : a total of 5 cases with debilitating chronic complications following filler injection who were referred to al-zahra hospital, isfahan are presented in this report. results : the outcome of treatment for two ...

Single- and multispecies biofilms formed by six drinking water-isolated bacterial species were used to assess their susceptibilities to sodium hypochlorite (SHC). In general, multispecies biofilms were more resistant to inactivation and removal than single biofilms. Total biofilm inactivation was achieved only for Acinetobacter calcoaceticus single-species biofilms and for those multispecies bi...

background recent evidences have revealed that in more than 65% of microbial infections, biofilms have critical roles. the ability of yeasts to form biofilms on surface of medical devices such as urine catheters is an important reason of the capability of these microorganisms to cause human disease. objectives the aim of this study was to isolate and identify yeasts on the surfaces of urine cat...

AIM The effect of photodynamic antimicrobial chemotherapy (PACT) on oral biofilms was evaluated. METHODS Biofilms formed in vitro were treated with sensitizer (S) and/or light (L) in the test (S+L+) and control (S-L-, S+L-, S-L+) groups. Additionally, 21 volunteers wore intraoral devices and the biofilms formed on each side of the device were referred to as S+L+ or S-L- groups. RESULTS Sign...

results the combination of bismuth ethanedithiol with ciprofloxacin showed synergistic inhibitory effect on the p. aeruginosa biofilm formation. the combination of bismuth ethanedithiol ciprofloxacin, ceftazidime and imipenem showed synergistic inhibitory effects on the biofilm formation. furthermore, the combination of bismuth ethanedithiol, imipenem and ceftazidime did not show any synergisti...