Cyclothymic disorder is a chronic and impairing subtype of bipolar disorder, largely neglected in pediatric research. Consequently, it is rarely diagnosed clinically despite potentially being the most prevalent form of bipolar disorder. Lack of attention has added to confusion about the diagnosis and clinical presentation of cyclothymic disorder. In pediatric studies, cyclothymic disorder is co...

BACKGROUND The relative contribution of demographic, lifestyle and medication factors to the association between affective disorders and cardiometabolic diseases is poorly understood. AIMS To assess the relationship between cardiometabolic disease and features of depresion and bipolar disorder within a large population sample. METHOD Cross-sectional study of 145 991 UK Biobank participants:...

INTRODUCTION: Bipolar disorder is a recurring chronic characterized by mood, state, and energy fluctuations. Individuals differ in symptoms, course, severity, response to treatment. It critical know the current knowledge of evolving pharmacological psychological strategies bipolar disorder. 
 Primary Objective: To compare assess prescribing pattern psychotropic agents affective with mania ...

BACKGROUND Heterogeneity within the diagnostic construct of bipolar disorder is most likely an obstacle to discovering its causes. Phenomena in the bipolar spectrum, including rapid cycling, cyclothymia, and affective instability of borderline personality, may be important markers of etiologic heterogeneity. Rapid switching of mood may be central to these phenomena. METHODS We performed a cas...

BACKGROUND Sleep disturbance in bipolar disorder can be both a risk factor and symptom of mood episodes. However, the associations among sleep and clinical characteristics, function, and quality of life in bipolar disorder have not been fully investigated. METHODS The prevalence of sleep disturbance, duration, and variability, as well as their associations with mood, function, and quality of ...

Objective: This study was conducted to compare the profile of temperament and character dimensions in patients with major depressive disorder and bipolar mood disorder with a control group. Method: In this causal-comparative study, the population consisted of 2 clinical groups (major depressive disorder and bipolar mood disorder) and a non-clinical group. The sample was 193 individuals (77 pati...

The lifetime prevalence of bipolar I disorder in the United States is reported to be between 1% and 1.6%; the prevalence of bipolar II disorder is estimated to be 0.5%. A more recent study, however, demonstrated an overall rate of 3.4%. Bipolar disorder is a lifelong debilitating and potentially fatal illness characterized by changes in mood, cognition, energy levels, behavior, and perception a...

OBJECTIVE Persistent neurocognitive deficits have been described in bipolar mood disorder. As far as we are aware, no study have examined whether the cognitive impairment is presented in the same way in a Brazilian sample. METHOD Cognitive function of 66 patients with bipolar disorder (32 with depressive symptoms and 34 euthymic) and 28 healthy subjects was examined using a complete cognitive...