Objective(s): Studies have mainly assessed the effect of hyperglycemia on18F-fluorodeoxyglucose (FDG) uptake in the brain. In this study, we assessed the FDG uptake of the brain not only in normo- and hyperglycemia but also in hypoglycemia to compare the effect of various blood glucose levels on regional FDG uptake in the brain. Methods: </...

Introduction: Meningioma is usually a benign brain tumor, but sometimes with aggressive course. The aim of this study was to assess the ability of 201Tl Brain SPECT to differentiate the pathologic grade of meningioma preoperatively. Methods: Thirty lesions in 28 patients were evaluated in this study. Early (20 minutes) and late (3 hours) brain SPECT images were performed and early u...

introduction: meningioma is usually a benign brain tumor, but sometimes with aggressive course. the aim of this study was to assess the ability of 201tl brain spect to differentiate the pathologic grade of meningioma preoperatively. methods: thirty lesions in 28 patients were evaluated in this study. early (20 minutes) and late (3 hours) brain spect images were performed and early uptake ratio...

 Carcinosarcoma is a rare type of cancer that is composed of a mixture of sarcomatous and carcinomatous elements. Pulmonary carcinosarcoma has a 25% five-year survival rate with a prognosis poorer than other non-small cell lung carcinomas. Herein, we report a case of pulmonary carcinosarcoma and its 18F-FDG PET/CT findings. A 61-year-old male patient presented with brain symptoms, including hea...

Objective(s): 99mTc-TRODAT-1, which binds to the dopamine transporter, could be used to image the dopaminergic system in diagnosis of Parkinson’s disease (PD). PD can be classified into two groups: late onset Parkinson’s disease (LOPD) and early onset Parkinson’s disease (EOPD). In this study we tried to determine the TRODAT SPECT findings in EOPD as compared to LOPD.Methods: Fifteen patients w...

Introduction: 99mTc-MIBI has been proposed for use as an imaging agent for various tumors, including breast cancer, lung cancer, lymphomas, melanomas and brain neoplastic lesions. Brain tumors are very common and radiotherapy being major part of treatment following surgery. After radiotherapy, deteriorating clinical status can be due to either radiation necrosis or recurrent tumor. Comput...

introduction: 99mtc-mibi has been proposed for use as an imaging agent for various tumors, including breast cancer, lung cancer, lymphomas, melanomas and brain neoplastic lesions. brain tumors are very common and radiotherapy being major part of treatment following surgery. after radiotherapy, deteriorating clinical status can be due to either radiation necrosis or recurrent tumor. computed tom...

Uptake transporters in brain microvascular endothelial cells (BMECs) are involved the penetration of basic (cationic) drugs such as diphenhydramine (DPHM) into brain. Lipopolysaccharide (LPS)-induced inflammation alters expression levels and activities uptake transporters, which change DPHM A microdialysis study showed that unbound brain-to-plasma partition coefficient ( K p,uu,brain ) for LPS ...

Introduction:Amphetamines are central nervous system (CNS) stimulant substances and amphetamine abuse is considered a growing problem in our country. Previous studies revealed destructive effects of amphetamines on metabolism, perfusion and structure of brain. The aim of current study was evaluating regional cerebral blood flow (rCBF) disturbances in methamphetamine (MA) abuser...

introduction:amphetamines are central nervous system (cns) stimulant substances and amphetamine abuse is considered a growing problem in our country. previous studies revealed destructive effects of amphetamines on metabolism, perfusion and structure of brain. the aim of current study was evaluating regional cerebral blood flow (rcbf) disturbances in methamphetamine (ma) abusers using brain per...