نتایج جستجو برای: cancer cell
تعداد نتایج: 2332371 فیلتر نتایج به سال:
Objective(s): Development of molecules that specifically recognize cancer cells is one of the major areas in cancer research. Human epidermal growth factor receptor 2 (HER2) is specifically expressed on the surface of breast cancer cells. HER2 is associated with an aggressive phenotype and poor prognosis. In this study we aimed to isolate RNA aptamers that specifically bind to HER2 overexpressi...
تحقیقات مختلف اثبات نموده اند که رشد و محتوای بیوشیمیایی روتیفرها می تواند تحت تاثیر نوع غذا و غلظت مواد غذایی تغییر نماید. ریز جلبک ها به عنوان یکی از منابع غذایی مهم برای کشت روتیفرها به ویژه از لحاظ شاخص های نظیر رشد، بقا، میزان پروتئین، چربی و اسیدهای چرب، ضروری می باشند. لذا تحقیق حاضر جهت مقایسه جلبک خشک (کلرلای پودری) و جلبک های تازه (ایزوکرایسیس گالبانا و نانوکلروپسیس آکولاتا) بر رشد، ت...
One of the emerging therapeutic strategies for targeted therapy of cancer is the use of chimeric proteins. The p28 peptide has the ability of selective entrance and activating apoptosis in breast cancer cells. The NRC antimicrobial peptide showed cytotoxic activity on various breast cancer including drug-resistant variants but also normal cell lines. Here we designed a chimeric protein consiste...
One of the emerging therapeutic strategies for targeted therapy of cancer is the use of chimeric proteins. The p28 peptide has the ability of selective entrance and activating apoptosis in breast cancer cells. The NRC antimicrobial peptide showed cytotoxic activity on various breast cancer including drug-resistant variants but also normal cell lines. Here we designed a chimeric protein consiste...
objective: thymoquinone (tq), as the main component of nigella sativa plant, shows anticancer properties. this study was aimed to evaluate the combined effect of tq and tamoxifen (tam) on viability and apoptosis of human breast cancer cell lines. materials and methods: in this experimental study, estrogen positive mcf-7 and estrogen negative mda-mb-231 human breast cancer cell lines were induce...
adipocytokines, hormones secreted from adipose tissue, have been shown to be associated with many cancers such as breast, prostate and colorectal cancer. recent studies have indicated that resistin and visfatin, two of these adipokines have high level plasma concentrations in colorectal cancer patients and may be promising biomarkers for colorectal cancer. the aim of this study was to identify ...
nanotechnology has slowly but steadily revolutionized the diagnosis, imaging and treatment of cancer. detecting cancer at earliest stages, locating the tumor at different areas in the body and specific delivery of the drugs to malignant cells including surgically inaccessible tumors are the core areas of medical and pharmaceutical research across the world. in this endeavour, nanodevices have e...
objective: in an attempt to develop safer and more effective gene therapy approaches as a realistic treatment for various forms of cancer, researchers are increasingly using tumor-specific promoters (tsp) to drive the expression of the gene of interest and eradicate cancer cells. in this study, for the first time we introduce the oct-4 promoter as a cancer-specific promoter with a high efficacy...
Background and purpose: Breast cancer is the most common cancer in woman. About one million new cases are diagnosed every year worldwide. Many researchers are interested in anti-cancer effects of natural products. In this research, cytotoxic effects of Crocus caspius extract against breast cancer and normal cell lines were investigated and total phenols and flavonoids were also determined. Mat...
Aims Because cancer is the leading cause of death worldwide, finding a better way to treat it seems essential. Doxorubicin is one of the most common drugs in the treatment of cancer, which has many negative and toxic effects. Therefore, efforts to produce effective anticancer drugs through screening natural compounds, such as animal toxins continue. This study aimed to evaluate the effect of Na...
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