background and objectives: urinary tract infections (utis) are of the most common bacterial diseases worldwide. we investigate the antibiotic susceptibility patterns of escherichia coli (e. coli) strains isolated from pediatric patients with community acquired urinary tract infection (uti) to find a clinical guidance for choosing a right empirical antibiotic in these patients. materials and met...

abstract background: pseudomonas aeruginosa is one of the most common gram negative bacteria involved in nosocomial infections. presence of extended-spectrum beta-lactamases (esbls) genes, play an important role in induction of resistance in beta-lactamase producing species to beta lactam antibiotics. frequency of resistance to these antibiotics is increasing. in this study, antibiotic sensitiv...

With the occurrence of extended-spectrum beta-lactamases (ESBLs) in Pseudomonas aeruginosa being increasingly reported worldwide, there is a need for a reliable test to detect ESBLs in clinical isolates of P. aeruginosa. In our study, a total of 75 clinical isolates of P. aeruginosa were studied. Nitrocefin tests were performed to detect the beta-lactamase enzyme; isoelectric focusing electroph...

Carbapenemase-producing Enterobacteriaceae (CPE) are rapidly spreading worldwide. Early detection of fecal CPE carriers is essential for effective infection control. Here, we evaluated the performance of a meropenem combined disk test (CDT) for rapidly differentiating CPE isolates directly from rectal swabs. The screening method was applied for 189 rectal swabs from hospitalized patients at hig...

Background and Objective: Beta-lactamases are the most important factors in the resistance to beta-lactam antibiotics among gram-negative bacteria, especially Klebsiella pneumoniae. Nowadays, the prevalence of infections caused by extended-spectrum β-lactamases (ESBLs)-producing K. pneumoniae is increasing, as one of the emerging health problems throughout the world. This study aimed to investi...

background :   imipenem-resistant gram negative bacteria, resulting from metallo-beta-lactamase (mbls)-producing strains have been reported to be among the important causes of nosocomial infections and of serious therapeutic problem worldwide. because of their broad range, potent carbapenemase activity and resistance to inhibitors, these enzymes can confer resistance to almost all beta-lactams....