نتایج جستجو برای: crocin

تعداد نتایج: 615  

Journal: :DARU Journal of Pharmaceutical Sciences 2014

2016
Jaroslaw Szlichta

Functional Dependencies (FDs) are commonly used in data cleaning to identify dirty and inconsistent data values. However, many errors require user input for specific domain knowledge. For example, let us consider the drugs, Advil and Crocin. FDs will consider these two drugs different because they are not syntactically equal. However, Advil and Crocin are synonyms as they are two different drug...

Journal: :Horticulturae 2023

Saffron is the world’s most coveted spicy plant that has medicinal value. Currently, due to diverse types of difficulties in growing this outdoor, tendency produce it indoor been increased. Optimized conditions for saffron plants not fully determined so far. This study was conducted investigate interactive effects two growth regulators (PGRs), including gibberellic acid (GA3) and γ-aminobutyric...

Objective: Crocinisa saffron constituent with a potent anti-oxidant activity. The present study investigated the effects of crocin and insulin treatments (alone or in combination) on cardiac function and pathology in diabetic rats. Materials and Methods: Diabetes was induced by intraperitoneal (i.p.) injection of streptozotocin (STZ, 50 mg/kg). Thereafter, crocin (5, 10 and 20 mg/kg, i.p.), sub...

Objectives: Crocin, a constituent of saffron and yellow gardenia, possesses anti-nociceptive effects. In the present study, we investigated the effects of intra-fourth ventricle injection of crocin in a rat model of orofacial pain. The contribution of opioid system was assessed using intra-fourth ventricle injection of naloxone, an opioid receptor antagonist. Materials and Methods: A guide cann...

Hossein Hosseinzadeh, Soghra Mehri, Somaye Heidari,

Introduction: D-galactose (D-gal) is well known as an appropriate agent to induced aging effects in the in vivo and in vitro models. In the present study, we selected crocin, the main constituent of Crocus sativus L. (Saffron), against D-gal cytotoxicity in human neuroblastoma SH-SY5Y cells. Materials and Methods:  Cells were pretreated with crocin (25-500 µM) for 24 h and then expos...

Journal: :مجله دانشگاه علوم پزشکی کرمانشاه 0
houshang najafi kermanshah zaynab mohamadi yarijani ali pourmotabed seyed hamid madani seyed abolhasan seyedzadeh

background: the aim of this study was to investigate the protective effects of crocin against tissue damages and leukocyte infiltration induced by renal ischemia/reperfusion. methods: in this experimental study, 35 male wister rats weighing 250-300 g were randomly divided into 5 groups; 1. operated controls, but no vessel occlusion was considered and passed during equivalent reperfusion period ...

Journal: :مجله دانشگاه علوم پزشکی کرمانشاه 0
seid- ershad nedaei department of neurosciences, tehran university of medical sciences, iran ali pourmotabbed department of physiology, school of medicine kermanshah university of medical sciences, iran maryam aeenfar student research committee, kermanshah university of medical sciences, iran zahra seifi student research committee, kermanshah university of medical sciences, iran

background: the cholinergic system plays an important role in learning and memory. administration of crocus sativus (saffron) or its constituent, crocin, facilitates the formation of memory. based on above findings, in the current study the effect of crocin in antagonizing retrograde amnesia induced by scopolamine, a cholinergic receptor antagonist, in rats was investigated by using shuttle box...

Journal: :acta medica iranica 0
bahareh naghizadeh department of pharmacology, physiology and pain research centers, school of medicine, jundishapur university of medical sciences, ahvaz, iran. mohammad taghi mansouri department of pharmacology, physiology and atherosclerosis research centers, jundishapur university of medical sciences, ahvaz, iran. behnam ghorbanzadeh department of pharmacology, faculty of medicine, jundishapur university of medical sciences, ahvaz, iran.

the study aimed to investigate the protective effects of crocin (cro) against streptozotocin (stz)-induced oxidative damage in rat striatum. animals were randomly divided into four groups (five each). group 1 (sham) were treated with normal saline (2 ml/kg, p.o.). group 2 (stz-lesioned or lesion) were injected with icv-stz (3 mg/kg bilaterally, on day 1 and 3) and treated with normal saline (2 ...

Journal: :avicenna journal of phytomedicine 0
mina taati division of physiology, department of basic sciences, faculty of veterinary medicine, urmia university, urmia 57153-1177, iran amir erfanparast division of physiology, department of basic sciences, faculty of veterinary medicine, urmia university, urmia 57153-1177, iran esmaeal tamaddonfard division of physiology, department of basic sciences, faculty of veterinary medicine, urmia university, urmia 57153-1177, iran hamid ghasemi division of physiology, department of basic sciences, faculty of veterinary medicine, urmia university, urmia 57153-1177, iran

objective: crocin and safranal, as the major constituents of saffron, have many biological activities. this study investigated the effects of crocin and safranal on yawning response induced by intracerebroventricular (i.c.v.) injection of histamine in rats. materials and methods: in ketamine/xylazine-anesthetized rats, a guide cannula was implanted in the right ventricle of the brain and yawnin...

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