Introduction: Nitric oxide (NO) is a neuronal messenger molecule in the central nervous system, which is generated from L-arginine by nitric oxide synthase (NOS) and involves in many important opioid-induced effects. Our previous studies revealed that Cuminum cyminum interestingly reduces morphine sensitization, tolerance and dependency in male mice. Therefore, in the present study, the effe...

Objectives: Diabetes is one of the most common metabolic diseases in the world. It affects 6.6% of world population and about 3 million individuals in Iran. Nowadays chemical and herbal medicines are widely prescribed to cure obesity. In Iran, cumin (Cuminum Cyminum L.) is a plant used in traditional medicine to cure obesity, and some of the new studies have suggested that cumin has a role in d...

Objective(s): Black cumin (Nigella sativa) belonging to Ranunculaceae family has a long history of medicinal use in various folk and traditional systems of medicine, including Iranian traditional medicine (ITM). These valuable medicinal seeds have been used traditionally against a variety of diseases such as dyspepsia, diabetes, headache, influenza and asthma. In addition, several scientific in...

introduction: nitric oxide (no) is a neuronal messenger molecule in the central nervous system, which is generated from l-arginine by nitric oxide synthase (nos) and involves in many important opioid-induced effects. our previous studies revealed that cuminum cyminum interestingly reduces morphine sensitization, tolerance and dependency in male mice. therefore, in the present study, the effect ...

Background Thymoquinone is one of the active ingredients of black cumin (Nigella sativa L.) essential oil possessing antiinflammatory, antineoplastic, neuroand hepatoprotective properties. Some of these properties were attributed to an antioxidant activity of thymoquinone, which seems to be unlikely from its structure. Because the lipophilic thymoquinone exhibits a structural similarity with th...

Water stress may affect the growth, physiology, morphology, biochemistry, and productivity of Nigella sativa (black cumin), a medicinal aromatic plant. Measuring these parameters under various irrigation regimes could provide useful information for successful genotype selection breeding. Therefore, agronomically significant features were evaluated in ten black cumin genotypes (Afghanistan, Paki...

Cumin leaf are medicinal plants that used as treatment and useful for health. contain secondary metabolites, one of which is flavonoids. Flavonoids the largest phenolic compounds found in function antioxidant, antibacterial, antiviral, anti-inflammatory, antiallergic, anticancer activities. The flavonoid content a plant can be affected by drying temperature manufacture simplicia. purpose this s...

A common problem with vegetable production in drought areas is low crop stand, but germination data are limited and inconsistent for cumin. Different priming methods positively affect the enhancement of seed seedlings growth, especially under stress conditions. The objective this study was to assess effects different treatment (unprimed seeds as control, hydro-priming, salicylic acid, jasmonic ...

cumin (cuminum cyminum) is an annual suitable for the dry and semi-dry areas of iran. recently, farmers have chosen to plant cumin because it requires less water and growth time. however, at harvest time, the resistance of cumin seed to shatter is low and, if careful attention is not paid to this fact, a major portion of the crop can be lost. when the connection force of the seed decreases, see...