Order picking is the process of retrieving products from storage in response to a specific customer order. Although this process’ design has significant impact on warehouse global performance, a practical-oriented design procedure is still lacking in literature. This paper presents a novel order picking system design methodology based on Design for Six Sigma approach, that aims to assist design...

Research on practical design verification techniques has long been impeded by the lack of published and yet detailed error data. Over the last few years we have systematically collected design error data from a number of academic microprocessor design projects. We present an analysis of this data and report on the lessons learned in the collection effort.

this study concerns the scope to improve water flooding in heterogeneous reservoirs. we used an existing, in-house developed, optimization program consisting of a reservoir simulator in combination with an adjoint-based optimal control algorithm. in particular we aimed to examine the scope for optimization in a two-dimensional horizontal reservoir containing a single high permeable streak, as a...

generally, a typical problem which is crucial in a manufacturing system is increasing the production rate.  to cope with the problem, different types of techniques are used in companies by trial and error which imposes high costs on them. using simulation as a tool for assessing the effect of alterations on the performance of the overall system might be significant. this paper considers a simul...

abstract human insulin-like growth factor i (higf-i) is a kind of growth factor with clinical significance in medicine. the major objective of this study is over- production of recombinant human insulin-like growth factor i( rhigf-i) through a developed process by recruiting effective factors in order to achieve the most recombinant protein. up to now e. coli expression system has been widely us...

There is increasing interest in the use of design patterns for model transformations, and a number of such patterns have been proposed. In this paper we survey previous work on transformation design patterns, discuss one pattern in detail, and identify priorities for future research.