conclusions the application of 5-ht1a, 5-ht2, 5-ht3, 5-ht4, 5-ht6 and 5-ht7 receptor antagonists, applied at concentrations lower than 1.0 µm did not modify the efs-induced contraction and relaxation responses, whichsuggests the unlikely involvement of endogenous 5-ht in mediating responses to efs in the described test conditions. materials and methods segments taken from the rat duodenum, jeju...

OBJECTIVE To estimate the cost-utility of bio-electric stimulation therapy (Posifect) compared to standard care in elderly patients with chronic, non-healing wounds of > 6 months duration, from the perspective of the National Health Service (NHS) in the UK. METHODS Clinical and resource use data from a 16 week clinical evaluation of bio-electric stimulation therapy among patients who had reca...

Gastroparesis is a chronic disabling condition of impaired gastric motility that results in decreased quality of life. Currently available medical therapy consists of prokinetic and/or antiemetic therapy, dietary modifications, and nutritional supplementation. For patients with medication-resistant gastroparesis a non-pharmacological therapy, gastric electric stimulation, has evolved over the l...

OBJECTIVE To investigate the feasibility of unsupervised community use of an array-based automated setup functional electrical stimulator for current foot-drop functional electrical stimulation (FES) users. DESIGN Feasibility study. SETTING Gait laboratory and community use. PARTICIPANTS Participants (N=7) with diagnosis of unilateral foot-drop of central neurologic origin (>6mo) who were...

Discomfort experienced during surface functional electrical stimulation (FES) is thought to be partly a result of localized high current density in the skin underneath the stimulating electrode. This article describes a finite element (FE) model to predict skin current density distribution in the region of the electrode during stimulation and its application to the identification of electrode p...

objectives: the purpose of this study was to evaluate whether intra-canal application of controlled direct electric current (dec) could accelerate the amount of orthodontic tooth movement (otm) in young adult mixed breed dogs. methods: fourth premolars of both jaws of five young adult mixed breed dogs were divided into two groups of control and experimental groups. orthodontic force was applied...

Computer models can make transcranial electric stimulation a better tool for research and therapy.

In order to support swallowing, the efficacy of functional electrical stimulation for different stimulation settings of the submental musculature has been investigated. The stimulation was administrated at rest and synchronously to voluntary initiated swallows. The onset of a swallow was detected in real-time by a combined electromyography/ bioimpedance measurement at the neck in order to trigg...