We examined 170 formalin-fixed paraffin-embedded samples from esophageal squamous cell carcinoma patients. All subjects live in Mazandaran province, a region with high incidence rate of esophageal cancer and have become known as the “Asian Esophageal Cancer Belt”. Samples were tested for HPV-DNA by MY09/11 and Gp5+/6+ general primers using nested PCR. Of the 170 ESCC samples, 86 (50.6%) were ma...

Human papillomavirus (HPV) DNA has been identified in esophageal carcinomas. However, the incidence of HPV varies significantly in different geographical locations. In this study, neoplasms from Turkmen Sahra, a region in Golestan province in northeast part of Iran, with a high incidence of squamous cell carcinoma were analyzed for the presence of HPV DNA. Turkmen Sahra is located in the cancer...

malignant tumors of pancreas are usually primary neoplasms and pancreatic metastases are rare findings. we are reporting a case of squamous cell carcinoma (scc) of the esophagus with pancreatic metastasis. a 59-year old woman was admitted with chief complaint of abdominal pain and mass. she was a known case of esophageal scc since 4 years before when she had undergone transthoracic esophagectom...

most patients with gastrointestinal cancers refer to the health centers at advanced stages of the disease and conventional treatments are not significantly effective for these patients. therefore, using modern therapeutic approaches with lower toxicity bring higher chance for successful treatment and reduced adverse effects in such patients. the aim of this study is to evaluate the effect of av...

abstract background: esophageal cancer is one of the major malignancies, with various epidemiological aspects in recent years in developing countries, including increased prevalence and variations of pathologic patterns. this may be due to increasing rates of barrett’s esophagus, gastroesophageal reflux, smoking and obesity. this study was performed from 1991 to 2005 in order to evaluate variou...

telomerase activation is one of the main pathways to immortalize cancer cells. in many kinds of cancer cells, this special reverse transcriptase stabilizes and elongates telomeres and prevents telomere erosion that naturally occurs in every cell division. esophageal cancer is the fifth most frequent cause of cancer death worldwide, and is highly associated with alcohol, smoking, cultural habits...

methods: we examined 170 formalin-fixed paraffin-embedded samples from esophageal squamous cell carcinoma patients. all subjects live in mazandaran province, a region with high incidence rate of esophageal cancer and have become known as the “asian esophageal cancer belt”. samples were tested for hpv-dna by my09/11 and gp5+/6+ general primers using nested pcr. results: of the 170 escc samples, ...

introduction: esophageal squamous-cell carcinoma (scc) is one of the most common malignancies in iran. to reduce the incidence of esophageal scc, it is important to recognize the controllable risk factors and prevent them. celiac disease is widely known as a possible risk factor for esophageal scc.  thus, we decided to assess the frequency of celiac disease in esophageal scc patients in north e...