background: bone marrow-derived mesenchymal cellscan transdifferentiate into cardiomyocyte cells and improveheart function after transplantation. since biomaterials canimprove the cell retention in the site, cell survival and differentiation,heart tissue engineering is now being explored as anapplied solution to support cell-based therapies and increasetheir efficacy for myocardial diseases. ch...

Left ventricular mass, fractional shortening, and end systolic wall stress (mechanical indices) measured by echocardiography and the response of fractional shortening and end systolic wall stress to the infusion of isoproterenol (0.02 microgram/kg/min for 5 min) (a non-mechanical index) were studied in 57 patients (mean (SD) age 49(8)) with essential hypertension. Nineteen patients had subnorma...

OBJECTIVES This study examined left ventricular performance in relatively unselected hypertensive patients by use of physiologically appropriate midwall shortening/end-systolic stress relations. BACKGROUND Supranormal left ventricular function has been reported in hypertensive patients, possibly due to an artifact of mismatching endocardial rather than midwall fractional shortening to mean le...

identification and monitoring of cardiovascular abnormalities in this group of patients require sensitive and efficient techniques. In another PC HIV report, there was unacceptable variability of many M-mode cardiac measurements, including fractional shortening, between the local and central institutions. The 95% predictive interval for fractional shortening was “–10% to 8% indicating that a fr...

BACKGROUND To assess the reliability of pediatric echocardiographic measurements, we compared local measurements with those made at a central facility. METHODS AND RESULTS The comparison was based on the first echocardiographic recording obtained on 735 children of HIV-infected mothers at 10 clinical sites focusing on measurements of left ventricular (LV) dimension, wall thicknesses, and frac...

Background—To assess the reliability of pediatric echocardiographic measurements, we compared local measurements with those made at a central facility. Methods and Results—The comparison was based on the first echocardiographic recording obtained on 735 children of HIV-infected mothers at 10 clinical sites focusing on measurements of left ventricular (LV) dimension, wall thicknesses, and fracti...

Background—To assess the reliability of pediatric echocardiographic measurements, we compared local measurements with those made at a central facility. Methods and Results—The comparison was based on the first echocardiographic recording obtained on 735 children of HIV-infected mothers at 10 clinical sites focusing on measurements of left ventricular (LV) dimension, wall thicknesses, and fracti...

Macrophages are found in the heart as part of the inflammatory response. To determine whether macrophages could contribute to myocardial dysfunction, rat ventricular myocytes were isolated and cocultured with elicited peritoneal macrophages in media containing tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, or endotoxin for 4 h. Cardiac myocytes were electrically stimulated, and fractiona...

STUDY OBJECTIVE To examine the relation between left atrial (LA) function and exercise performance. DESIGN AND SETTING Retrospective study at a referral cardiopulmonary exercise laboratory in a university hospital. PATIENTS Forty-one patients with recent myocardial infarction. INTERVENTIONS M-mode echocardiography and cardiopulmonary exercise testing combined with radionuclide ventriculog...