in this paper, two patients with severe dysphagia and esophageal stricture secondary to epidermolysis bullosa are presented and discussed. they are siblings of an affected family. primary resection and anastomosis had been performed previously in both patients, but dysphagia had recurred. we treated these patients with free jejunal graft to the esophagus with excellent results. both patients ar...

abstract the leg is a complex district with functions of weightbearing support, stability, and motility. the management of extensive and complex defects is more challenging and often results in leg amputation or shortening. leg amputation is a severe mutilation that alters the patient’s work and social life by limiting ambulation and self-sufficiency. during a 3 years period we treated four pat...

abstract background: several case studies have described the use of the superficial inferior epigastric artery (siea) flap as a pedicled flap for reconstruction of upper and lower ex tremities, or a free fasciocutaneous flap when a large amount of skin coverage is required for hemifacial atrophy, breast or head and neck reconstruction. apparently, the anatomical findings of previous studies are...

diabetes is a major health problem worldwide. type ii diabetic patients are reported to have higher ferritin and lower vitamin c concentrations. considering the role of ascorbic acid in carnitine biosynthesis and the limited information on free carnitine correlations with ferritin and vitamin c levels in diabetic patients without microvascular complications, this case-control study was conducte...

apoptosis is a complex network of biochemical and molecular pathway with fine regulatory mechanisms that control the death event during several pathological situations in multi cellular organisms. it is the part of normal development that occurs in a variety of diseases and is known as aberrant apoptosis. pancreatic β cell apoptosis is also a pathological feature which is common in both type 1 ...

We show that the free energy of the topological string admits a certain pole structure by using the operator formalism. Combined with the results of Peng that proved the integrality, this gives a combinatoric proof of the Gopakumar–Vafa conjecture.