Background: Influenza virus is a major infectious pathogen of the respiratory system causing a high degree of morbidity and mortality annually. The worldwide vaccines are decided and produced annually by World Health Organization and licensed companies based on the samples collected from all over the world. The aim of this study was to determine phylogenecity and heterogenecity of the circulati...

objective this is the first report of cns involvement by the new influenza virus (influenza a [h1n1]) in iran. the patient was a 10-year-old boy with chief complaints of fever, malaise, and cranial nerve involvement, resulting in respiratory muscle paralysis and intubation. this shows that the new influenza virus, as well as the seasonal flu, can cause neurologic complications; however, the sev...

Background: Both influenza A virus (IAV) and respiratory syncytial virus (RSV) cause acute respiratory infection (ARI) in infants and young children. This study was conducted to determine Influenza A virus and its co infection with RSV among the hospitalized children with ARI. Methods: A total of 153 throat samples of the hospitalized young children aged between below one year and 5 years with...

conclusions clinical signs and symptoms presented by patients infected with the influenza a h1n1 virus were similar to those described for seasonal influenza, although with more gastrointestinal disorders. results among the 232 enrolled cases, 126 patients (54.31%) were male and 106 patients (45.89%) were female. real time reverse rt-pcr test revealed that 18.1% of suspected children were posit...

results out of 253 cases confirmed for influenza a (h1n1), 9 women and 11men had died. amongst these cases the minimum and maximum age was3.5 and90 years, respectively. also, from the 20 confirmed cases of influenza a (h1n1) that had died, 16 cases had at least one underlying disease. conclusions there was no significant association between mortality of confirmed cases of influenza a (h1n1) and...

Background: A new pandemic influenza A (H1N1) emerged in April 2009, causing considerable morbidity and mortality. Since mutations in the haemagglutinin (HA) may influence the antigenicity and pathogenicity of the virus, continued epidemiological and molecular characterization for the effective control of pandemic flu and developing of more appropriate vaccine is crucial. Objective: To monitor ...

background: both influenza a virus (iav) and respiratory syncytial virus (rsv) cause acute respiratory infection (ari) in infants and young children. this study was conducted to determine influenza a virus and its co infection with rsv among the hospitalized children with ari. methods: a total of 153 throat samples of the hospitalized young children aged between below one year and 5 years with ...

conclusions a(h1n1)pdm09 viruses, identified in this study in shiraz, iran, contained 5 site specific mutations and were susceptible to oseltamivir. results our results revealed that a(h1n1)pdm09 viruses present in these samples were susceptible to oseltamivir, and contained 5 site specific mutations (v13g, v106i, v241i, n248d, and n369k) in na gene. these mutations correlated with increasing e...