osteoarthritis is the most common joint disease.the main pathologic manifestation of disease is local destruction of cartilage in diarthrodial joint. new bone formation in marginal surface of the joint is a sign progressive disease. many systemic and local factors are introduced in initiate and progression of osteoarthritis include: age, sex, weight, race, genetic background, bone densitometry,...

conclusions both l-prp and l-prf could be used to effectively promote the healing of articular cartilage defects of the knee. results mean macroscopic scores of the treated defects were higher than the controls at all sampling times with significant differences (p < 0.05) observed between l-prf treated and control defects (10.13 vs. 8.37) and l-prp treated and control defects (10 vs. 8.5) at 4 ...

articular cartilage, the load-bearing tissue of the joint, has limited repair and regeneration ability. the scarcity of treatment modalities for large chondral defects has motivated researchers to engineer cartilage tissue constructs that can meet the functional demands of this tissue in vivo. cartilage tissue engineering requires 3 components: cells, scaffold, and environment. owning to their ...

Articular cartilage, the load-bearing tissue of the joint, has limited repair and regeneration&nbsp;ability. The scarcity of treatment modalities for large chondral defects has motivated researchers&nbsp;to engineer cartilage tissue constructs that can meet the functional demands of this tissue in&nbsp;vivo. Cartilage tissue engineering requires 3 components: cells, scaffold, and environment. ...

ultrastructural changes in immature articular carilage were studied after treatment of 5-weeks-old rats with ofloxacin, a fluoroquinolone, and in magnesium deficiency.we concluded that quinolone-induced arthropathy is probably due to chelation of functionally available magnesium in joint cartilage as magnesium deficiency in joint cartilage could impair chondrocyte-matrix- interaction which is m...

background : in recent years tissue engineering developed to replace or repair damaged tissues using cell and biomaterial. one of the most important fields of tissue engineering is simulation of in vivo micro environment of body tissues. this study aimed to develop culture chamber and cell biomaterial sheet engineering for the reconstruction of cartilage tissue. methods : stainless steel cultur...

introduction osteochondritis is a joint condition in which bone underneath the cartilage of a joint destroys due to lack of blood flow. then bone and cartilage can break, causing pain and sometimes affecting joint motion and skin around the involved joint might be swollen and tender. osteochondritis occurs most commonly in the knee, but also occurs in elbows, ankles and other joints. decreased ...

Purpose Joint cartilage degradation is one of the early outcomes in juvenile idiopathic arthritis (JIA). One of the primary goals of rheumatic treatment is to prevent joint destruction. We therefore need sensitive methods to evaluate cartilage thickness. Ultrasonography (US) has shown to be a reliable tool in the assessment of joint cartilage in rheumatic disease. We have previously been able t...

Objective : To study the correlation between ankle and knee cartilage morphology to test the hypothesis that knee joint cartilage loss in gonarthritis can be estimated retrospectively using quantitative MRI analysis of the knee and ankle and established regression equations; and to test the hypothesis that sex differences in joint surface area are larger in the knee than the ankle, which may ex...