background: the activity and toxicity of etoposide in women with recurrent ovarian cancer was evaluated in a case series of women with recurrent ovarian cancer who had measurable disease, methods: all patients had plior platinum-based chemotherapy and developed progressive disease, etoposide was given as 50mg/day for 21 days every 4 weeks until progression of disease or prohibitive toxicity, be...

Nearly 50 % of newly diagnosed colorectal cancer, affect people over 70 years of age. Inclusion of older patients in clinical trials has been extremely rare. As a result, there is debate on how to manage these patients because it is still unclear how to balance the therapeutic advantages and toxicities. For patients who do not have comorbid conditions, with performance status (P.S.) 0–1, treatm...

basal cell carcinoma (bcc) is the most common cancer among humans, and the standard treatment is surgery. other modalities are reserved as a second line of treatment. topical chemotherapy may be used in primary bcc. systemic chemotherapy has no role in the primary treatment of bcc, although it may be efficacious in metastatic cases. we report the case of a patient with persistent recurrent bcc ...

OBJECTIVE Platinum-based doublet chemotherapy is considered the standard of care for advanced non-small cell lung cancer (NSCLC). However, prognosis after recurrent or progressive disease following first-line chemotherapy is usually poor. Maintenance chemotherapy, second line treatment and even third line chemotherapy are available for patients with advanced NSCLC. Unfortunately, few patients a...

background: small cell lung cancer (sclc) is a highly aggressive tumor.   objective: to evaluate the survival and time to progression of patients with sclc admitted to a chest disease center in istanbul, turkey.   methods: based on the reports of a pulmonary oncology clinic, data regarding performance status (ps), clinical stage of disease, treatment, time to progression and survival of 67 pati...

OBJECTIVE The majority of patients with advanced epithelial ovarian cancer (EOC) will experience a recurrence after primary chemotherapy and receive second-line chemotherapy. Patients who have a disease-free interval >6 months (platinum-sensitive) will often receive multiple chemotherapy regimens. Therefore, our goal was to assess the effectiveness and medical costs of chemotherapy for platinum...

this study was designed to assess the role of first-line chemotherapy with 5-fu and platinum in the treatment of advanced or recurrent cervical cancer, ten patients with advanced or recurrent cancer of the cervix, with no prior chemotherapy were entered in phase ii trial, from oct. 2000 to nov. 2001. eight patients were treated with cis-platinum (50 mg/m2 over 60 minutes in first day) followed ...

Background: Small cell lung cancer (SCLC) is a highly aggressive tumor. Objective: To evaluate the survival and time to progression of patients with SCLC admitted to a chest disease center in Istanbul, Turkey. Methods: Based on the reports of a pulmonary oncology clinic, data regarding performance status (PS), clinical stage of disease, treatment, time to progression and survival of 67 patients...